Re: left handed twist on breast cancer
- From: "a.c." <aquachimp@xxxxxxxxxxxxxxxxxxxxxxxxx>
- Date: 2 Jan 2006 13:49:29 -0800
dave @ stejonda wrote:
> In message <1136229056.175520.89530@xxxxxxxxxxxxxxxxxxxxxxxxxxxx>, a.c.
> <aquachimp@xxxxxxxxxxxxxxxxxxxxxxxxx> writes
> >I'm not sure if this news item has yet featured within the uk, even
> >though I heard mention of the British Medical Journal, (on Belgium news
> >programme) but apparantly left handed women are 40% more likely to get
> >breast cancer. How odd!
> >
>
> Here's the lead-in to the article from the BMJ site
>
> BMJ 2005;331 (15 October), doi:10.1136/bmj.331.7521.0-d
> "Left handed women have more than twice the risk of developing breast
> cancer before reaching the menopause than right handed women. In a
> population based prospective case-cohort study of more than 12 000 women
> who were followed up for 16 years, Ramadhani and colleagues (p 882) also
> found that the risk of postmenopausal breast cancer was similar for left
> handed and non-left handed women. A plausible pathophysiological
> explanation is the existence of common intrauterine hormonal influences
> that determine both cerebral lateralisation and risk of breast cancer."
>
> and here's the Comment from the article:
>
> "We found that left handed women are more than twice as likely to
> develop premenopausal breast cancer as non-left handed women. This risk
> is compatible with left handedness being a marker of constitutional risk
> rather than of environmental risk as with postmenopausal breast cancer.
>
> Our findings among premenopausal women may be compatible with a stronger
> association in women with a normal body mass index, as high body mass
> index is a particular risk factor for postmenopausal breast cancer.
> However, our data did not allow for a robust analysis of this issue.
>
> The origin of the association may lie in intrauterine exposure to
> steroid hormones, as supported by data showing a higher prevalence of
> left handedness in women with intrauterine exposure to
> diethylstilbestrol.4 Although the underlying mechanisms remain elusive,
> our results support the hypothesis that left handedness is related to
> increased risk of breast cancer."
>
> I don't think I'm allowed to, and since this is off-topic nor should I
> quote any more than that here but if individuals want I guess I could
> email a pdf of the article to them, (but only up until 6pm tomorrow -
> after that I'll be away for a few days).
>
> --
> dave @ stejonda
You win tonight's box of chocolates for most information provided.
Erm, I don't have your address and besides, the postage costs more than
the pralines themselves, so the box might be minus the chocs.
That aside, there's the matter of what is or is not off topic.
1) Does the BMJ publication not come under the term Media?
I wrote on the assumption it did.
2) Is it only valid (on topic) to refer to something currently in the
media (were "currently" has a decent retro-lifespan) and therby
disallowed to mention something that perhaps should be, though opinion
on "should" may be problematic?
Have a nice few days off (-:
.
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