Anti-spam measures in Mail

I want to give different email addresses to my contacts so that, when
one of them lets a spammer get the address I have given to that contact,
I can change that address without having to tell all my other contacts.
So, if my domain is username.me.uk.invalid [without the invalid,
obviously] and I send an email to Fred, I want Fred to see the email as
coming from Fred@xxxxxxxxxxxxxxxxxxxxxx so that he will use that address
when replying. I can fix it with my ISP so that email sent to lots of
different addresses will all arrive in the same mailbox.

But how do I manage this within Mail? As far as I can see, Mail requires
each outgoing email to be sent from an existing account. In the
"Account" field of the new message it gives you a drop-down list of the
accounts you have set up, so that you can choose one. It doesn't seem to
be possible to insert an address which does not belong to any existing
account. If that's right, presumably I have to create a separate account
within Mail (as well as all the aliases with my ISP) for each contact.
Am I missing something here? There must be a cunning way round the
problem which I'm too dim to see.

--
To email, pull out the weeds
.

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