Re: Avian Flu, BSE and FMD




"Pat Gardiner" <patgardiner@xxxxxxxxxxxxxx> wrote in message
news:devd8s$m4t$1@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>
> " Jill." <news@xxxxxxxxxxxxxxxxxxxxxxxxx> wrote in message
> news:43132874$0$1312$ed2619ec@xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
>>
>> "Pat Gardiner" <patgardiner@xxxxxxxxxxxxxx> wrote in message >
>>> The virus has already mutated. That stable door can't be closed.
>>
>> http://www.promedmail.org/pls/promed/f?p=2400:1001:16306418344298210439::NO:
>> :F2400_P1001_BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,30213
>> An outbreak of highly pathogenic avian influenza A (H5N1) has recently
>> spread to poultry in 9 Asian countries. H5N1 infections have caused 52
>> human deaths in Viet Nam, Thailand, and Cambodia from January 2004 to
>> April
>> 2005. Genomic analyses of H5N1 isolates from birds and humans showed 2
>> distinct clades with a non-overlapping geographic distribution. All the
>> viral genes were of avian influenza origin, which indicates absence of
>> reassortment with human influenza viruses. All human H5N1 isolates tested
>> belonged to a single clade and were resistant to the adamantane drugs but
>> sensitive to neuraminidase inhibitors. Most H5N1 isolates from humans
>> were
>> antigenically homogeneous and distinct from avian viruses circulating
>> before the end of 2003. Some 2005 isolates showed evidence of antigenic
>> drift. An updated nonpathogenic H5N1 reference virus, lacking the
>> polybasic
>> cleavage site in the hemagglutinin gene, was produced by reverse genetics
>> in anticipation of the possible need to vaccinate humans.
>
> I think you overlooked telling us about the following paragraph from the
> same piece.
>
> Quote
>
> Introduction
> ----------
> Highly pathogenic avian influenza viruses of the H5N1 subtype are
> circulating in eastern Asia with unprecedented epizootic and epidemic
> effects. 9 Asian countries reported H5N1 outbreaks in poultry in 2004:
> Cambodia, China, Indonesia, Japan, Laos, Malaysia, South Korea, Thailand,
> and Viet Nam. Between 2004 and the 1st 3 months of 2005, a total of 89
> laboratory-confirmed human infections, 52 of which were fatal, were
> reported to the World Health Organization (WHO) by public health
> authorities in Viet Nam, Thailand, and Cambodia. These records indicate
> that this outbreak of human H5N1 infections is the largest documented
> since
> its emergence in humans in 1997. Efficient viral transmission among
> poultry
> caused the virus to spread regionally, leading to the loss of >100 million
> birds from disease and culling. In contrast, human-to-human transmission
> of
> the virus is exceptional but has been described, most recently in a family
> cluster in Thailand.
>
> Unquote
>
> Do be careful, Jill!
>
> I can read and quickly pick up when you are being selective. It is only a
> question if I have enough time to check every reference.

I gave the reference and I gave the summary
There is nothing in the rest to contradict the statement that the virus has
not mutated into a human to human transmittable form without the presence of
poultry
Go and do some research -- google news "avian influenza" will lead you to
plenty of good sources

>
> Do you have a close relative that is a vet? Surely you don't have a
> British SVS vet in the family?

Is this your new fixation?
Juvenile



.



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