Re: Delayed Treatments for Prostate Cancer
- From: "George Conklin" <georgeconklin1@xxxxxxxxxxxxx>
- Date: Sun, 20 Aug 2006 11:31:22 GMT
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Are you talking about,
"Incidence of Initial Local Therapy Among Men With
someProstate
Cancer in the United States " ?
All that that article finds is that we are overtreating
already.men
with
low
grade prostate cancer - something which we all know
Butalready
A major journal does not publish articles about what is
known.
LOL... yes they do - all the time. Confirmational studies.
They're
actually much easier to get published than are novel ideas.
thanhey,
thanks
for expressing your ignorance.
The study cited is based on real-world experience rather
difference.afrom
self-selected group of volunteers. That is always a
cite
Good to know for future reference - so from now on, whenever I
morea
evidence.study
based on the SEER database, you'll have to accept it as strong
You have a real bias against large data bases. You seem want
fewchoosing.variables and confuse that with moe variables...those of your
you
Oooh, no, I love large databases. I'm merely pointing out that you
are
stating it is excellent to use the SEER database so when I use it
later
will, of course, accept it as great evidence. (yes, I'm setting you
up
here, so tread carefully).
These are real-world outcomes, not those projected from a
whichhundred
self-selected men in a so-called 'clinical' study.
It was actually nothing more than a retrospective review,
WEAKERis
agreemuch
weaker than a randomized control trial would be.
Incorrect.
No, not incorrect. It was a retrospective study. If you don't
with
that, then you don't understand the terminology being used.
Your assumption that using data on real-world out comes is
ou(your
term) than some small-scale clinical study with self-selected
volunteers
is
pure BIAS. I know the terms used, but your biases are so horrid y
interventionevencannot
accept anything but what you want.
It is well established that strongest evidence is prospective. Yes,
largersmaller numbers of a prospective study are generally stronger than
In fact, it is NOT an established fact. It is just an old wive's talenumbers of a retrospective study. That's not my opinion - it's an
established fact.
This is your personal bias
no. an established fact.
and one accepted in your industry to try to limit authority and research
dollars. Not keeping track of real-world outcomes is criminal. To have
treatment protocols for millions of men with prostate cancer based on a
sample of a few hundred is a disgrace and you know it.
There are no "treatment protocols". Treatment is based on the best
available data. We have excellent long term data on the results of
interventions, including pretty conclusive proof that surgical
for prostate cancer results in an improved overall and disease specific
mortality.
And that is what the whole point of the PIVOT and other studies are trying
to prove, but have no done so yet. The overall decline in the death rate in
general is very strong in UK, for example, but they do not screen
asymptomatic men there for prostate cancer. The study you cite from Sweden,
which, by the way, I have, and you worship, showed a 3% possible effect in
10 years, certainly a pitiful difference. The fact you believe the current
data is strong is another one of your biases in favor of what you claim you
make your money at. You report not science but self-intrest.
.
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