Re: The ultimate cause of aging

Kermit wrote:
On Mar 5, 1:34 am, Tim Tyler <seemy...@xxxxxxxxxxxxxx> wrote:
Iain wrote:

"Aging is a product of evolutionary neglect, not intent."
http://www.youtube.com/watch?v=wEyguiO4UW0
Evolution /does/ care.

There is a resource conflict between maintenance and reproduction,
and reproduction considered to be more important.

So evolution starves maintenance mechanisms and puts its resources
into making babies - naturally resulting in senescence as damage
fails to get repaired.

Len Hayflick is wrong about this issue - and Aubrey should
not be quoting him approvingly.

Yes. It's not very advantageous for a dog if it has a mutation
allowing it to live to be 20, but it's not selected against.

An exceptionally long lived animal would waste a lot
of energy and developmental resources by fixing damage
unnecessarily. Those resources would otherwise be spent on
reproductive goals - so the exceptionally long lived animals
would normally be out-competed by ones with ordinary lifespans.

That's the common situation, anyway. Dogs are a bit of
a weird example, since they are largely selected by humans,
who /might/ be deliberately selecting for longevity.

> OTOH, a human that lives to be 80 lives to help his/her
> children raise the grandkids, and pass on knowledge that
> the tribe (usually all close kin) can use to their advantage.

Probably true among our ancestors. Western societies often
marginalise their elderly, and stick them in homes :-|
--
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