Can any old earther refute common genetic ancestry?

Comparative genetics and population genetics provide compelling
evidence for common genetic ancestry. All genome differences in all
extant biological life can be broken down to population isolation and
microevolution, where microevolution is the processes of mutation and
drift and selection. And mutations include point substitutions,
indels, conversions, and chromosome aberrations. Can anybody show me
an extant genome that cannot be explained by population isolation and
microevolution?

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