Re: Why don't mitochondria have junk DNA?


John Harshman wrote:
> rev.goetz wrote:
>
> > John Harshman wrote:
> >
> >>Selection for fast replication? That's the usual idea for bacteria, but
> >>do mitochondria have to replicate that often compared to the nucleus of
> >>the same cell? That would depend on the lifetime of a mitochondrion and
> >>its standing population in the cell. I'll have to look that up.
> >>
> >>If not that, then what?
> >>
> >>There are mitochondria with junk. In fact the control region has been
> >>duplicated several times in different groups of birds, and one of the
> >>copies is clearly non-functional. So it does happen. But why so rarely?
> >
> >
> > Junk DNA is an extavagant byproduct of evolutionary processes because
> > the rate of neutral mutational insertions from various types of
> > repeated sequences appears to be significantly more frequent than the
> > fixation rate of all mutational deletions. And I recall that only
> > diploid cells have the mechanisms that generate various types of
> > repeated sequences. (I do not have the time to look up the reasons for
> > this.)
>
> You would seem to be talking about unequal crossing over. That's only
> one of a host of processes that generate new sequences.

Unequal crossing over is only one of a few mechanisms that help to
generate non-coding DNA in eukaryotes.

>
> > Concerning some junk DNA in mitochondria, this could have occurred by
> > DNA transfer from the nuclear genome to the mitochondrial genome. I am
> > not sure if I have heard of cases of DNA transfer from the nuclear
> > genome to the mitochondrial genome, but I know that I heard of several
> > examples of gene transfer from the mitochondrial genome to the the
> > nuclear genome. So I would not be surprised to see if the reverse ever
> > happened.
>
> I don't know of any such case. Like I said, the only mt junk I know of
> involves a duplication of a mitochondrial region.

I missed that you said it was a duplication of a mitochondrial region,
so scratch what I said about DNA transfer from the nuclear genome to
the mitochondrial genome.

In general, mutational insertions/duplications are more likely to occur
in eukaryotes compared to prokaryotes. And as someone said earlier in
this topic, many eukaryotes are not harmed by an accumulation of DNA in
the genome. So many insertions/duplications are neutral in terms of
fitness in many eukaryotes, but in many prokaryotes a large increase in
genome size causes a decrease in fitness. So natural selection prevents
a large increase of "useless DNA"in many prokaryotes.

.

Relevant Pages

  • Re: Why dont mitochondria have junk DNA?
    ... >>producing their own junk. ... > often in mitochondria) is junk removal. ... > of mitochondrial proteins from the mitochondria into the main ... happens to get copied into the nuclear genome in functional form, ...
    (talk.origins)
  • Re: Why dont mitochondria have junk DNA?
    ... >> the mitochondrial genome. ... >> in eukaryotes compared to prokaryotes. ... > that strong in mitochondria, though that would depend on their ... natural selection favoring a compact genome could still be ...
    (talk.origins)
  • Re: Why dont mitochondria have junk DNA?
    ... > Unequal crossing over is only one of a few mechanisms that help to ... > generate non-coding DNA in eukaryotes. ... >>>Concerning some junk DNA in mitochondria, ... >>>DNA transfer from the nuclear genome to the mitochondrial genome. ...
    (talk.origins)
  • Re: Why dont mitochondria have junk DNA?
    ... >> the nuclear genome. ... > There is no such DNA in the typical mitochondrion. ... Plant mitochondria vary a lot in size ... "similar pattern of convergence with a gene sized chunk of nonconserved ...
    (talk.origins)
  • Re: Real scientist (Einstein) versus fake scientists (neo-Darwinists)
    ... > My next question - what is mitochondrial DNA? ... Mitochondria are organelles that, so far as I understand exist ... in nearly all eukaryotic cells. ... > seperate replication process, or are they copied from the nucleic DNA, ...
    (talk.origins)
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