Postdoctoral position on simulations of mitochondrial toxicity in AIDS therapy

Simulation of the Mitochondrial Toxicity of Nucleoside Analogs

The Virginia Bioinformatics Institute (VBI) invites applications for an
AIDS Therapy Modeler Postdoctoral Associate to work in the research
group of Dr. David C. Samuels on a project funded by NIH to study the
mitochondrial toxicity of AZT (zidovudine or Retrovir) and other
nucleoside analog drugs used in the treatment of HIV/AIDS. The
candidate will be involved in computational modeling of the toxicity
mechanisms of these drugs, within a biomedical modeling research group
and in collaboration with a laboratory group that is carrying out
experiments on these drugs. This position will involve further
development of the existing simulation, interaction with the lab-based
collaborators and supervision of one graduate student. For an example
of the simulation, see our recent paper in Am. J Physiol. Cell
Physiol., vol 288, pp 989-1002, 2005.

The successful candidate must have a PhD in a biological, mathematical
or computational field; experience in biochemical or cell biology
modeling; demonstrated creativity, independence, high motivation, and
good communication skills, demonstrated experience in developing
publications in peer reviewed high impact scientific journals based on
individual research; and possess strong work habits and the ability to
work independently as well as with research group. Preferences will be
given to candidates having knowledge or experience with Mathematica,
Systems Biology Markup Language (SBML), or an equivalent modeling or
simulation system; or knowledge of mitochondrial biology or of
antiviral therapy.

Duration of the appointment may be up to two years renewable annually
dependent on satisfactory performance and continuation of funding.
This position will hold the special research faculty rank of
Postdoctoral Associate. For more information on the university ranks
for special research faculty, please review the Special Research
Faculty Handbook located at
http://www.provost.vt.edu/web_pages/faculty_handbooks.html.

Interested candidates should submit a letter of interest and CV upon
applying through www.jobs.vt.edu searching by posting number 042829.
Successful candidates invited for interviews will be required to have
three letters of recommendation sent by the author directly to the
department as part of the application process. Review of applications
will begin for this position on Monday, August 22, 2005.

Compensation is commensurate with experience.

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has built
an internationally recognized scientific program with significant
extramural funding. Areas of strength among the 16 research groups at
VBI include infectious diseases, ranging from the molecular to the
population scale, systems biology approaches to study stress response
in several organisms, modeling and simulation of biological networks,
functional genomics, metabolomics, proteomics and
bioinformatics/computational biology. For a closer look, visit us at
www.vbi.vt.edu.

An Equal Opportunity/Affirmative Action Institution

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