Re: Botox for BOH

Interesting, isn't it?
This was presented at the American Urological Association meeting. The
evidence is still very preliminary, with only small groups of patients
having been treated. Botox paralizes smooth muscle and as you know
smooth muscle tone of the prostate and bladder neck account for the
"dynamic" component of obstruction. Relaxation of smooth muscle is the
mechanism of action of Flowmax and other alpha blockers.
The only problem is that Botox's duration of action averages 6 months.
So it would need to be a repetitive treatment. Too early to be
recommended, but an interesting and minimally invasive idea... We will
have to wait and see what happens. I am sure next year's congress will
be filled with papers on this.

Fernando Gómez Sancha
http:/drgomezsancha2.blogspot.com

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Relevant Pages

  • Re: Botox for BOH
    ... with only small groups of patients ... Botox paralizes smooth muscle and as you know ... The only problem is that Botox's duration of action averages 6 months. ...
    (sci.med.prostate.bph)
  • Re: Botox for BOH
    ... Is any doctor in New York City doing Botox shots for BPH? ... with only small groups of patients ... Botox paralizes smooth muscle and as you know ... The only problem is that Botox's duration of action averages 6 months. ...
    (sci.med.prostate.bph)