Re: Acid, Base, Water & Temp. Balances?


Bryan Heit wrote:
> kumar wrote:
> > Bryan Heit wrote:
> >>Basically, restored oxygen flow activates
> >>your immune cells, which then begin to produce damaging chemicals
> >>(including oxidants). This results in increased damage to the ischemic
> >>tissues.
> >
> > Can the cause of this damage be acidosis or lactic acidosis at the site
> > of damage? Starving a tissue of Oxygen can encourage lactic acid
> > production.
>
>
> Some of the damage is due to acidosis of the tissue, particularly when
> the tissue is starved for oxygen over a long period of time (i.e. a
> transplanted organ). However, the damage caused by oxidant production
> tends to be the predominant form of damage. Keep in mind that it only
> takes a short period of time after blood flow is restored to eliminate
> acidosis. Oxidant production (and other damaging aspects of
> inflammation) can last for hours, or even days.
>
>
>
> > Let us check immunological side. Hill stations or higher altitudes are
> > considered to improve immunity. Will it be by pure air or less O2 at
> > higher altitude?
>
>
> I don't think this is correct. I am unaware of any study showing
> significant differences in immunity due solely to differences in
> altitude. Keep in mind that your body is remarkable able to adapt to
> changes in the environment - including differences in altitude. If you
> live for a time at increased altitude your body will adapt by increasing
> production of hemoglobin and red blood cell production. People who grow
> up at high altitudes will even develop "barrel chests"; which is a
> result of over development of lung size due to continued low oxygen
> partial pressures.
>
>
> > Anyway, can imbalance in any place of iron effect imbalance in fats
> > oxidation or its accumulation?
>
>
> A lack of iron causes several problem, almost all related to lack of
> oxygen movement through the body. One of the first problems associated
> with iron deficiency is anemia; a lack of red blood cells (or RBC's
> without sufficient hemoglobin). Mild anemia is associated with a
> continued feeling of tiredness and weakness (due to insufficient oxygen
> making it to your tissues). As iron levels drop further the anemia
> becomes more acute. Eventually this can reach a point where the patient
> becomes wasted, and more susceptible to infection. AFAIK this poor
> immunity and wasting is still due to a lack of oxygen in the blood,
> rather then defects in other metabolic pathways.
>
> Interestingly, many vegetarians suffer from mild anemia due to a lack of
> iron and other minerals normally ingested via meat consumption.
>
>
> > What about role of iron in heat
> > production on excess oxidation of fats? I feel iron can cause both
> > heating and cooling effects to body. ??
>
>
> The heat our bodies generate is a product of our metabolism. Some of
> these enzyme do contain iron, so in that context our body temperature is
> due, in part, to iron. Iron wouldn't play a role in cooling; our bodies
> cool themselves via sweating, not by reducing the basal metabolic rate
> (this is determined largely by our bodies energy demands).
>
> As for fat, it's "warming" effect is due to its insulatory effect.
> Unlike some animals (rodents, for example), humans don't have "brown
> fat", which is a specialized type of fat which generates heat. As such
> any warming we get from fat is due to the fact that fat acts like
> insulation, and lowers the rate that heat leaves our body.
>
>
> > Btw, what factors weakens or strengthen the immunity?
>
> Wow, there's a loaded question. The answer is "probably everything".
> Nearly everything you do, nearly every disease you get, every food you
> eat, every drug you use, has the potential to impact on your immune
> system to some extent. Some of these have very predictable effects,
> while the effects of others will depend on the individual.
>
>
>
> > Somewhere it is indicated that heat is produced due to fat deposits and
> > by their excess oxidations, but still it is unclear. Can fats be
> > imbalanced in cells membranes as lipo-protien or lipofusion deposits?
>
> Not really. There is a big difference between the chemical structure of
> fat, and the lipids which make up our membranes. Generally speaking,
> the types of molecules found in body fat are not found within our cell
> membranes. That said, changes in membrane lipid makeup can drastically
> alter then characteristics of cells. There are probably diseases
> related to this, but I don't know what they are off hand.
>
> Bryan

.

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