Proton Pump Inhibitors

Proton pump inhibitors (or "PPI"s) are a group of drugs whose main
action is pronounced and long-lasting reduction of gastric acid
production. They are the most potent inhibitors of acid secretion
available today. The group followed and has largely superseded another
group of pharmaceuticals with similar effects, but different mode-of-
action, called H2-receptor antagonists. These drugs are among the most
widely-selling drugs in the world as a result of their outstanding
efficacy and safety. Structurally, the vast majority of these drugs
are benzimidazole derivatives; however, promising new research
indicates that imidazopyridine derivatives may be a more effective
means of treatment.

http://bioisolutions.blogspot.com/2008/07/proton-pump-inhibitors-therapy.html
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