Re: Control (new / unique / detailed perspective)


- - -

[skipped pillpopper's avoidance of dealing
with whatever glucose anomaly he has,
including his avoidance of acknowledging
which glucose anomaly he has, along with
his incessant inappropriate inaccurate guilt-
tripping tripe he tosses ad infinitum]

Control?
http://prohuman.net/control.htm

The following offers hope, for those with
Insulinitis, the primary focus of the article,
but also, for those with Diminosis who cur-
rently use insulin injections as part of their
treatment, and for those with Cellosis who
currently use insulin injections (estimated
to be about 25% of persons with Cellosis
in America) along with oral meds / exer-
cise / diet and/or weight loss to deal with
that condition:

- - -
December 13, 2011

JDRF to Support ViaCyte's Development
of Innovative Encapsulated Beta Cell
Replacement Therapy

at prnewswire.com
http://tinyurl.com/encapsulated-beta-cell-insulin
- - -

Excerpts [with insert, not part of original article,
included in brackets]:

JDRF announced today its support of a pioneering ...
research program that is developing a first-of-its-kind
cell therapy ...

The therapy is a combination product that packages
immature cells made from human embryonic stem cells
(hESCs) that over time develop into mature pancreatic
hormone producing cells (pro-islet) including insulin-
producing cells. The research is an important step
toward producing an unlimited source of insulin-pro-
ducing cells that could serve as replacements for
those destroyed ...

.... funded by JDRF, the largest charitable funder of
T1D [Insulinitis] research in the world, the California
Institute for Regenerative Medicine (CIRM), and ViaCyte,
a San Diego, California-based biotechnology company ...

.... ViaCyte's program will provide a replenishable supply
of functional insulin-producing cells. Furthermore, pack-
aging the cells in a device ("encapsulation") creates a
physical barrier around the cells and has the potential to
protect the transplanted cells from immune rejection, and
may eliminate the need for chronic immunosuppressive
drugs.

The ultimate goal of this partnership is to help patients
with T1D [Insulinitis] restore their ability to regulate
blood glucose, thereby reducing or eliminating the need
for constant self-management and administration of
insulin.

"Encapsulation research is one of JDRF's priorities because
of the profound possibilities it holds for many avenues of
research for type 1 diabetes [Insulinitis]," said Julia Green-
stein, JDRF's assistant vice president for Cure therapies.
"We're excited about partnering with ViaCyte to explore
the use of encapsulated stem cell-based replacement.

This type of innovative therapy could revolutionize the
way people live with type 1 diabetes [Insulinitis], and
may also reduce the risk of dangerous complications
that often result from extreme high and low blood
sugars."

- - - end excerpts - - -

- - - - - - - - - - - - - - - - - - - - - - - - - -

Viacyte
http://www.viacyte.com/

Viacyte Technologies Overview
http://www.viacyte.com/tech/

Viacyte Stem Cell Engineering
http://www.viacyte.com/tech/engineering.html

Viacyte Cell Encapsulation
http://www.viacyte.com/tech/encapsulation.html

Viacyte Clinical Application
http://www.viacyte.com/trials/index.html

Excerpts [with inserts, not part of original article,
included in brackets]:

As beta cell loss is the primary pathogenesis of
insulin-dependent diabetes [Insulinitis], the disease
is a great candidate for cell replacement therapy.
To this end, ViaCyte?s lead cell therapy product,
called Pro-Islet?, is being developed to provide
replacement beta cells ...

Pro-Islet? cells for medical or clinical use are
expected to provide the same types of benefits
as intensive insulin therapy but without the
trouble of frequent blood sugar monitoring and
insulin injections, and without the risk of unsafe
hypoglycemic events.

Because Pro-Islet? is comprised of human cells
it uses natural biological mechanisms to respond
to blood sugar [glucose] levels.

Indeed, not only blood sugar [glucose] is moni-
tored and regulated by the pancreatic Islets of
Langerhans [in people without Insulinitis], but
numerous other activities in the blood, reflecting
the body?s overall physiological state, are also
relevant, and Pro-Islet? will respond to the full
array of inputs as well.

Likewise, the response of Pro-Islet? is not just
that of releasing insulin, but also includes the
full repertoire of beta cell functions that are
lost in [totally or near-totally in persons with
Insulinitis, in varying degrees with lessened
but continuing insulin production in persons
with Diminosis or Cellosis].

As Pro-Islet? will employ physiologically rele-
vant detection, and response to blood chemis-
tries on a continuous basis, as compared to
pharmaceutical insulin, it may well represent
a quantum advance in medical treatment [for
the conditions previously mentioned, although
of note, it does not address the insulin resistance
which underlies the causality of the high glucose
problem present in those with Cellosis, so it's
unclear the extent to which alterations in other
treatments will be required to mate to improve-
ments in insulin release in those with Cellosis].

- - - end excerpts - - -

- - - - - - - - - - - - - - - - - - - - - - -

- - -
Pro-Humanist FREELOVER
C.ure I.nsulinitis A.ssociation
http://prohuman.net/cureinsulinitisassociation.htm
- - -


.

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