Re: The secret of 'muscular' old age





The magic work is SECRET. I have seen those with some
scheme to alleviate old age. They all die on schedule.

On 14 Dec 2005 12:43:35 -0800, diarmidlogan@xxxxxxxxx wrote:

>http://news.bbc.co.uk/2/hi/health/4502862.stm
>
>Scientists believe they have found a way to enable the elderly to
>maintain muscle.
>
>Muscle is constantly being built and broken down, which works to
>maintain a balance in young adults.
>
>But as people age, the breakdown process is more successful than the
>muscle-building action.
>
>However French researchers, writing in the Journal of Physiology, say
>adding the amino acid leucine to old people's diets could help them
>keep muscle.
>
>Leucine is found in meat, soy, beans and legumes, among other foods.
>
>Once adults reach 40, they start to lose between 0.5 and 2% of their
>muscle each year.
>
>The team from the Human Nutrition Research Centre of Auvergne, in
>Clermont-Ferrand, France looked at the behaviour of proteins in muscle.
>
>
>As in all mammalian tissues, proteins are created (synthesised) from
>amino acids and digested (degraded) by enzymes.
>
>Straight after a meal, the rate of synthesis doubles, prompted by the
>arrival of a large amount of amino acids.
>
>The rate of the breakdown of protein is highest in-between meals.
>
>The difference between the two rates determines how much protein
>remains in the muscle.
>
>But, in older animals - and, it is believed, humans - the amino acid
>stimulus prompting synthesis is less effective, and the process slows
>down.
>
>However, the breakdown of proteins is not, leaving older animals with
>less protein than their younger counterparts.
>
>The researchers compared protein breakdown in young (eight-month-old)
>and old (22-month) rats.
>
>They discovered that the slow down in degradation that normally follows
>a meal does not occur in old animals, so there is excessive breakdown.
>
>But when the scientists boosted levels of one amino acid, leucine, the
>balance of synthesis and breakdown was restored.
>
>The team, led by Dr Didier Attaix, suggest the protein processing
>imbalance which comes with age results from defects in the complex
>machinery that breaks down muscle protein, and that leucine
>supplementation can fully restore correct function.
>
>He said: "Preventing muscle wasting is a major socio-economic and
>public health issue, that we may be able to combat with a leucine-rich
>diet."
>
>Dr Michael Rennie from the University of Nottingham Medical School at
>Derby told the BBC News website more research into the finding was
>needed.
>
>But he said older people could make changes to their diet now which
>could help them maintain muscle.
>
>"If they don't, they can fall over more easily; they can trip down
>stairs or fall in the bath."
>
>Dr Rennie said older people could act now, even before further research
>had been carried out.
>
>"Leucine is most abundant in meat, so it makes sense in terms of
>protein synthesis to eat meat.
>
>"As people get older, they tend to need to eat less. But people should
>maintain their protein intake as they age."


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