Pesticide Dangers to Human Health Carry Through Multiple Generations



NaturalNews.com
Originally published June 20 2008

Pesticide Dangers to Human Health Carry Through Multiple Generations
by David Gutierrez

(NaturalNews) A recent study conducted by researchers from the
University of Texas at Austin has uncovered evidence that the damage
done by pesticides may last for four generations or more.

Reproductive neuroendocrinologist Andrea Gore and evolutionary
biologist David Crews compared the sexual behavior of two different
groups of rats. One group of rats was a standard laboratory rat stock,
while the other group was descended from rats that had been subjected
to the hormone-disrupting effects of chemicals. Reproductive biologist
had injected the great-grandmothers of these rats with vinclozolin, a
common fungicide that is particularly popular among grape-growers.

Skinner's research had previously shown that the male descendents of
the rats who had been injected with vinclozolin developed various
reproductive and other difficulties later in life, including sperm
deficiencies, infertility, breast tumors and kidney disease.

All the rats in the Gore-Crews study were between 90 and 120 years
old, half were female and half were male. Males and females were
separated by a wire mesh, and then the researchers timed how long each
rat spent sniffing or bumping noses with rats of the opposite sex,
indicators of sexual interest.

The researchers observed no difference in how female rats were treated
by males, regardless of whether those females were descended of
injected rats or control rats. But females expressed significantly
less interest in males who were descended of vinclozolin-injected rats
than in males descended from control rats.

Researchers could not find any apparent health or fertility problems
in the rats descended of the injected females. This led them to
believe that certain chemicals function not to damage DNA, but instead
to permanently silence or reprogram normal genes to have abnormal
function. This type of change can be more long-lasting than a
mutation, which can be more easily bred out of a population through
mating with healthy animals.

Because the reproductive developmental processes of mammals are all
incredibly similar to each other, the researchers believe that similar
effects probably occur in humans exposed to toxic chemicals as well.





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