Green Tea May Prevent Prostate Cancer
- From: "sheila" <robomouseketer@xxxxxxxxx>
- Date: 31 Mar 2007 10:48:48 -0700
ANAHEIM, Calif.--After one year taking green tea catechins (GTCs),
only one in a group of 32 men at high risk of developing prostate
cancer were diagnosed with the disease, compared to nine out of 30 in
a control group. Italian researchers found epigallocatechin gallate
(EGCG) in GTCs targeted prostate cancer cells for death, without
damaging benign controls. The results were reported at the 96th Annual
Meeting of the American Association for Cancer Research in Anaheim,
Calif.
Italian researchers from the University of Parma, University of
Modena, Reggio Emilia and Saverio
Bettuzzi found Clusterin, a gene involved in prostate apoptosis, a
possible mediator of catechins' action. "EGCG induced death in cancer
cells, not normal cells, inducing Clusterin expression," said
Bettuzzi. The research subjects were aged 45 to 75 with high-grade
prostatic intraepithelial neoplasia--malignant lesions that are
prostate cancer precursors--for which no treatment had been given, and
who were not consuming green tea, tea-derived products or
antioxidants, or following anti-androgenic therapy. Intervention
subjects received 200 mg of GTCs (50 percent EGCG). The 30 percent
incidence rate of prostate cancer in the control group was consistent
with previous findings, as was the absence of significant side effects
or adverse reactions among the treated group.
For more information visit: http://www.prostacet.com/?aid=627156
.
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