Re: Benefits of flu vaccine overestimated in elderly people




David Wright wrote:
> In article <1136986469.575863.251830@xxxxxxxxxxxxxxxxxxxxxxxxxxxx>,
> PeterB <pkm@xxxxxxxxxxxxxxx> wrote:
> >
> >David Wright wrote:
> >> In article <1136311427.596450.19450@xxxxxxxxxxxxxxxxxxxxxxxxxxxx>,
> >> PeterB <pkm@xxxxxxxxxxxxxxx> wrote:
> >> >
> >> >Roman Bystrianyk wrote:
> >> >> "Benefits of flu vaccine overestimated in elderly people", Xagena,
> >> >> Italy, December 27, 2005,
> >> >> Link:
> >> >>
> >>
> >>http://www.xagena.it/news/medicinenews_net_news/44c62bd3f8177f420ed8cee90fdbc0a1.html
> >> >
> >> >This is clear evidence that flu vaccine studies have been biased in
> >> >favor of a positive outcome. A similar flaw in epidemiological studies
> >> >probably explains the utopia-like outcomes in children receiving
> >> >measles vaccine, particularly those already the beneficiaries of
> >> >positive environmental factors never adjusted for.
> >>
> >> My goodness, PeterB, you certainly do raise clutching at straws from
> >> a mere act of desperation to something resembling an art form.
> >
> >Thinking *is* a form of art, if you think about it.
>
> Have it your own way. You're no artist.

Can I get it without the pickles?

> >> Talk about comparing apples and oranges. For one thing, measles
> >> vaccination is nearly universal, and the tiny number of cases these
> >> days makes it quite clear (to everyone but the wilfully blind, like
> >> yourself) that it's working just fine.
> >
> >If I had a penny for every non sequitur you've posted since I've been
> >here, I'd have a few bucks by now. The fact an intervention is applied
> >doesn't prove it works.
>
> The fact that an intervention is applied and the desired result
> ensues, throughout an entire country, and when the intervention ceases
> to be used and the old result returns, is as close to proof as you're
> going to get outside of mathematics.

You've never proven any of that.

> If you think that's a non sequitur, that's your problem.

Non sequitur? No, it was an ipso facto.

> You were comparing flu vaccination to measles vaccination. That's not
> a legitimate comparison.

No, I was comparing sloppy accounting, or worse.

> First off, flu vaccine doesn't confer
> lifetime immunity, unlike measles vaccine (or, similarly, getting the
> measles). Flu changes every year; measles doesn't. Second, we've
> never tried to have everyone vaccinated for the flu, whereas virtually
> all children are vaccinated for measles.

Which does not mean we have not over-estimated the effectiveness of
both.

> >Since you don't have the study results to prove that it does, my
> >guess is as good as yours.
>
> No, it's not -- because I have evidence on my side, and all you have
> is speculation.

Your evidence is very low quality.

> Furthermore, just because I don't have the studies
> doesn't mean they don't exist, it means they don't exist in PubMed.
> Papers about measles vaccine, at least as of the time it was
> introduced, are too old to be in PubMed.

Talk about speculative.

> >My guess is that it "works" about 10% of the time.
>
> Your guess is obviously wrong, because a vaccine that only works 10%
> of the time would never confer herd immunity and measles would still
> be with us, barely abated.

Since measles mortality had already dropped by 95% (meaning a
substantial amount of morbidity, as well), the only indicator we have
for vaccine effectiveness is tally stroking, blood work, poor people
getting to the doctor, and a total absence of vaccine bias. You
believe in those fairy tales because the problem has gone away, but I
don't.

> >Without controlled studies, we just don't know. It's just as likely
> >as not that a variety of environmental factors are responsible for
> >the other 90% that remain free of infection, even after exposure (we
> >certainly have no forensic proof that people aren't being exposed,
> >now do we?)
>
> Since measles invariably breaks out when vaccination declines, I'd say
> we're still being exposed.

I agree we're still being exposed but I don't agree that measles
invariably breaks out when vaccination declines. Without controlled
studies, the impact of vaccine is guesswork.

> So, I don't know of these supposed "environmental factors" that
> appeared out of nowhere at the same time as vaccination and actually
> did all the heavy lifting.

Susceptability to viral disease has always been strongly related to
environment.

> >> The supposed "environmental
> >> risk factors" do not even enter into the matter.
> >
> >This brings to mind the self-balancing checkbook analogy. If I don't
> >look, I'll never be over-drawn. Does this mean that smoking never has
> >to cause lung cancer?
>
> No, it means you've never come up with a convincing argument for your
> "10% effectiveness" claim. The best you could muster was the idea
> that either measles was still infecting everyone, but so weakly that
> nobody noticed it (which still requires explanation, even if it were
> true) or that doctors and parents were so overwhelmed with the idea of
> vaccination that they all suddenly lost their minds and became unable
> to identify a case of the measles.

I've talked about the difficulty of diagnosis depending on the stage of
illness when (and if) a child is presented for medical evaluation. You
seem to think that children enter a doctor's office with a placard on
their forehead that reads: "I have a mild case of measles. Please
order bloodwork and report your findings to the dept. of health."

> "The vaccine works" is a much simpler explanation.

Believing the earth was flat was also pretty simple, but stupid.

> >> For one thing, you can't tell us what they are, and it's highly
> >> unlikely that they even exist, since if the vaccination isn't doing
> >> it, there should be lots of pockets of significant measles
> >> outbreaks every year. But there aren't.
> >
> >You love these non sequiturs, don't you? "If" and "should" open the
> >proverbial can of worms.
>
> Oh, then, by all means, open it, PeterB. Let your magnificent
> intellect show me the error of my ways.

I'm not here to show *you* anything. But you already know that.

PeterB

.



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