Re: Ontario-Studie

Hans-J. Tilsner wrote:

bei allen solchen "Studien" fehlt das Aufdröseln nach DM-Dauer und
beständigem Behandlungs-Erfolg.
Da wird der 1c von > 10 in den selben Topf geworfen wie der < 6.


--------------------------------------------------------------------------------------------------------------------------
The Lancet 2006; 368:29-36

DOI:10.1016/S0140-6736(06)68967-8

Relation between age and cardiovascular disease in men and women with
diabetes compared with non-diabetic people: a population-based retrospective
cohort study

Dr Gillian L Booth MD a b f , Moira K Kapral MD a c e f, Kinwah Fung
MSc f and Jack V Tu MD a d f

Summary

Background
Adults with diabetes are thought to have a high risk of cardiovascular
disease (CVD), irrespective of their age. The main aim of this study was to
find out the age at which people with diabetes develop a high risk of CVD,
as defined by: an event rate equivalent to a 10-year risk of 20% or more; or
an event rate equivalent to that associated with previous myocardial
infarction.

Methods
We did a population-based retrospective cohort study using provincial health
claims to identify all adults with (n=379?003) and (n=9?018?082) without
diabetes mellitus living in Ontario, Canada, on April 1, 1994. Individuals
were followed up to record CVD events until March 31, 2000.

Findings
The transition to a high-risk category occurred at a younger age for men and
women with diabetes than for those without diabetes (mean difference 14·6
years). For the outcome of acute myocardial infarction (AMI), stroke, or
death from any cause, diabetic men and women entered the high-risk category
at ages 47·9 and 54·3 years respectively. When we used a broader definition
of CVD that also included coronary or carotid revascularisation, the ages
were 41·3 and 47·7 years for men and women with diabetes respectively.

Interpretation
Diabetes confers an equivalent risk to ageing 15 years. However, in general,
younger people with diabetes (age 40 or younger) do not seem to be at high
risk of CVD. Age should be taken into account in targeting of risk reduction
in people with diabetes.
--------------------------------------------------------------------------------------------------------------------------

Es scheint wirklich nicht aufgeschlüsselt zu sein... allerdings ist Kanada
diabetologisch kein DritteWelt-Land und bei 379000 PErsonen dürfte man einen
guten Schnitt durch die Bevölkerung haben.
Die Verallgemeinerung auf "alle solche Studien" ist aber trotzdem etwas
gewagt.


Anja


.

Relevant Pages

  • Re: 5 Tips for Avoiding Cardiovascular Disease
    ... cardiovascular disease (CVD), folks wanting to avoid CVD have a need ... Only if the risk is 100%. ... The effect of diabetes on health is equivalent to ageing 15 years, ... category for cardiovascular disease * 15 years earlier than those ...
    (sci.med.cardiology)
  • Re: New test predicts damage from diabetes - article about AGEs
    ... > bringing about the various nasties we call diabetic complications. ... > advanced glycation end-products that will give a measure of the silent ... complications of diabetes they are the major cause of death and disability ... Low-molecular weight advanced glycation end products: markers of tissue AGE ...
    (alt.support.diabetes)
  • Long term progress
    ... Before I was diagnosed (in 2004 at age 62) I had for some time been ... Greatly reducing wheat products in my diet must have reduced ... It probably also helped to control and slow ... diabetes in her middle age, he would test my blood, and sometimes also ...
    (alt.support.diabetes)
  • Re: Richard Jewell Dies
    ... I had a relative die of diabetes and he didn't work from the age of 40 after ... Jewell was found dead in his west Georgia home. ... Jewell died of natural causes at the age of 44. ...
    (alt.true-crime)
  • Re: health effects of dietary AGEs
    ... damaging complications seen in diabetes. ... enhanced AGE ... association between dietary AGE intake and markers of systemic ... research suggests dietary AGE products do enter the blood stream, ...
    (alt.support.diabetes)