Re: New Drug?



My understanding would be yes, but not as completely as in a complete stem
cell transplant or BMT. The immunity would be compromised for a period of
time but would eventually recover. The risks inherent would be
managed/monitored very closely as they are high. (you definitely wouldn't be
riding public transit for a while)
Janice

"GaryA" <gary.aiken@xxxxxxxxxxxxxxxxxxxxx> wrote in message
news:Gvudnd5mQstzHnXYnZ2dnUVZ_hisnZ2d@xxxxxxxxxxxxxx
I wonder, does this mean you'd also lose all immunity to the bad stuff too?

Gary

Ross M. Greenberg wrote:
Revimmune works by temporarily
eliminating peripheral immune cells, including the immune cells causing
the
autoimmunity, while selectively sparing the stem cells in the bone
marrow.
Investigators at Hopkins discovered that stem cells uniquely have high
levels of a particular protective enzyme that can be measured in advance
of
therapy, which makes them impervious to Revimmune, and allows the
surviving
stem cells to give rise to the new immune system over 2 to 3 weeks. The
newly reconstituted peripheral immune system typically lacks the
misdirected
immunity to self-antigens, which is characteristic of autoimmune
diseases.



.



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