Re: A

On 5/9/2012 10:15 AM, Susan wrote:
x-no-archive: yes

On 5/9/2012 10:09 AM, Chris Malcolm wrote:

Especially when we all have google at our service.

http://www.bmj.com/content/333/7581/1267.short

"Anecdotes that provide definitive evidence"

BMJ 2006; 333 doi: 10.1136/bmj.39036.666389.94 (Published 14 December
2006)

"When a criminal is caught in the act, other evidence is
unnecessary. Should the same be true for adverse drug reactions?

Many adverse drug reactions are first reported anecdotally. Anecdotal
reports, by which we mean either individual cases or small case
series, are generally regarded as providing poor quality
evidence. They therefore usually require formal verification through
robust epidemiological studies or clinical trials, although a minority
are actually verified.1 However, we propose that some adverse drug
reactions are so convincing, even without traditional chronological
causal criteria such as challenge tests, that a well documented
anecdotal report can provide convincing evidence of a causal
association and further verification is not needed."

[snip]

"We have identified four types of spontaneously reported adverse
events for which causal or contributory attribution to the drug is
either irrefutable or demonstrable with a high level of confidence."


I guess that's why the CDC and the NIH collect anecdotal reports of
adverse drug reactions, among other things. The DATA is highly
informative about areas that need investigation.

Susan
STILL not data - Anecdotes provide possibilities, but NEVER data
.

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