Re: Vitamin D: Too Much May Erase Heart Benef

Perhaps the business model of supporting 21 ng/dL level is the support
of the grim reaper.
Granted this a small study below:




Am J Surg. 2011 Dec 27. [Epub ahead of print]

Effects of vitamin D deficiency in critically ill surgical patients.

Flynn L, Zimmerman LH, McNorton K, Dolman M, Tyburski J,
Baylor A, Wilson R,
Dolman H.

Department of Surgery,
Wayne State University,
School of Medicine, Detroit
Receiving Hospital, Detroit Medical Center,
Detroit, MI, USA.

BACKGROUND:
The incidence of vitamin D deficiency in critically ill patients is
reported to be up to 50%, with a 3-fold increase in predicted
mortality, but limited data exist concerning vitamin D deficiency
in critically ill surgical patients.

METHODS:
Sixty-six adult surgical intensive care unit patients who had
25-hydroxyvitamin D serum levels evaluated from
January 2010 to February 2011
were prospectively identified.
Patients were divided into groups according to
vitamin D level (<20 vs ≥20 ng/mL).

RESULTS:
Of the 66 patients evaluated, 49
(74%) had vitamin D levels < 20 ng/mL, and 17 (26%) had vitamin D
levels ≥ 20
ng/mL. Patients with vitamin D levels < 20 versus ≥ 20 ng/mL had
longer lengths
of hospital stay. Lengths of intensive care unit stay were clinically
longer,
although not significant. Infection rates tended to be higher (P = .
09), and a
higher incidence of sepsis was seen in the patients with vitamin D
levels < 20
ng/mL.

CONCLUSIONS:
Vitamin D levels < 20 ng/mL have a significant impact on
length of stay, organ dysfunction, and infection rates.
More data are needed on
the value of supplementation to improve these outcomes.

Copyright © 2011 Elsevier Inc. All rights reserved.

PMID: 22206852 [PubMed - as supplied by publisher]



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