Re: Regular use of aspirin/NSAIDS = increased risk of impotence



"Susan" wrote in message news:8u9fooFdn6U1@xxxxxxxxxxxxxxxxxxxxx

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http://www.jurology.com/article/S0022-5347(10)05203-1/abstract

Regular Nonsteroidal Anti-Inflammatory Drug Use and Erectile Dysfunction
• Joseph M. Gleason
,
• Jeffrey M. Slezak
,
• Howard Jung
,
• Kristi Reynolds
,
• Stephen K. Van Den Eeden
,
• Reina Haque
,
• Virginia P. Quinn
,
• Ronald K. Loo
,
• Steven J. Jacobsen
Received 20 January 2010 published online 21 February 2011.
Corrected Proof
• Abstract
•
Purpose

Previous data suggest a potential relationship between inflammation and
erectile dysfunction. If it is causal, nonsteroidal anti-inflammatory
drug use should be inversely associated with erectile dysfunction. To
this end we examined the association between nonsteroidal
anti-inflammatory drug use and erectile dysfunction in a large,
ethnically diverse cohort of men enrolled in the California Men's Health
Study.

Materials and Methods
This prospective cohort study enrolled male members of the Kaiser
Permanente managed care plans who were 45 to 69 years old beginning in
2002. Erectile dysfunction was assessed by questionnaire. Nonsteroidal
anti-inflammatory drug exposure was determined by automated pharmacy
data and self-reported use.

Results
Of the 80,966 men in this study 47.4% were considered nonsteroidal
anti-inflammatory drug users based on the definitions used and 29.3%
reported moderate or severe erectile dysfunction. Nonsteroidal
anti-inflammatory drug use and erectile dysfunction strongly correlated
with age with regular drug use increasing from 34.5% in men at ages 45
to 49 years to 54.7% in men 60 to 69 years old with erectile dysfunction
increasing from 13% to 42%. The unadjusted OR for the association of
nonsteroidal anti-inflammatory drugs and erectile dysfunction was 2.40
(95% CI 2.27, 2.53). With adjustment for age, race/ethnicity, smoking
status, diabetes mellitus, hypertension, hyperlipidemia, peripheral
vascular disease, coronary artery disease and body mass index, a
positive association persisted (adjusted OR 1.38). The association
persisted when using a stricter definition of nonsteroidal
anti-inflammatory drug exposure.

Conclusions
These data suggest that regular nonsteroidal anti-inflammatory drug use
is associated with erectile dysfunction beyond what would be expected
due to age and comorbidity.
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That's BS, I've been taking baby aspirin for 35 years and at 73, I can still hit a home run with my morning wood.


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Relevant Pages

  • Re: Regular use of aspirin/NSAIDS = increased risk of impotence
    ... Regular Nonsteroidal Anti-Inflammatory Drug Use and Erectile Dysfunction ... With adjustment for age, race/ethnicity, smoking ...
    (alt.support.diabetes)
  • Regular use of aspirin/NSAIDS = increased risk of impotence
    ... Previous data suggest a potential relationship between inflammation and erectile dysfunction. ... nonsteroidal anti-inflammatory drug use should be inversely associated with erectile dysfunction. ... Nonsteroidal anti-inflammatory drug use and erectile dysfunction strongly correlated with age with regular drug use increasing from 34.5% in men at ages 45 ... These data suggest that regular nonsteroidal anti-inflammatory drug use is associated with erectile dysfunction beyond what would be expected due to age and comorbidity. ...
    (alt.support.diabetes)