Re: Glycolation - resistance?



On Thu, 22 Apr 2010 01:16:54 -0700, "Paul M. Cook" <pmcook@xxxxxxx>
wrote:


"Lono" <londotpennelli@xxxxxxxxx> wrote in message
news:hqop1f$sdn$1@xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Age 72
5' 8" and 170#
Diagnosed T2 10 years ago
Otherwise healthier than I ever expected
Metformin 1000mg, 2x
Byetta 10mcg, 2x

My eating habits are those of a non-diabetic teenager, with high carb
intake (lots of sugars, too) and postprandial peaks near 200.

My A1c is typically 5.5-5.7 -- really!

Is it possible that my hemoglobin is somehow less susceptible to
glycation? What else could account for the anomaly?

Thanks,


The HBA1C can be fooled, from my studies. If you are prone to short
duration spikes you can maintain a low A1C. However, studies have shown
that even short duration spikes can cause a lot of physical damage.
Neuropathy is not so much caused by high BG as it is by spikes in glucose.

As always, I am not a doctor. I express only what I have learned.

Very true, as your A1c reduces so the effect of postprandials vs.
fasting numbers increases. This is self-evident when explained - which
it often isn't.

My A1c went UP with improved BG control - because I was not only
bringing down the postprandial highs but reducing the
post-postprandial lows.

That's one factor but there are others, some people can accurately
predict their A1c from spot readings, others may run reliably and
repeatably low or high - not only diabetics. Probably has to do with
longer or shorter lived blood cells.
.