Re: Can there be an afternoon liver dump?



On Fri, 28 Aug 2009 08:41:35 -0400, "Steve Hopkins" <123@xxxxxxx>
wrote:


"Alan S" <loralgtweightandcarbs@xxxxxxxxx> wrote in message
news:ko8e959o3ee9ck6fl89n1apmgfc6451giv@xxxxxxxxxx
: On Thu, 27 Aug 2009 15:27:16 -0400, Susan <susan@xxxxxxxxxxxx> wrote:
:
:
: <snipped>
: I think gluconeogenesis is only part of it. Whether glycogen is
: previously stored as the result of carbohydrate input or
: gluconeogenesis of protein, a "liver dump" (use whatever technical
: words you wish to substitute, Gys) occurs when stored glycogen, form
: any source, in the liver is released as a source of energy between
: meals to become blood glucose, rather than the blood glucose being
: provided immediately after eating carbohydrates.

Maybe it's too early for me, but that last part just didn't make sense.
Could you perhaps restate what you mean in a different way?

I wrote a different version here, maybe that will help:
http://loraldiabetes.blogspot.com/2009/02/i-ate-nothing-why-are-my-bgs-high.html
:
: In that sense "liver dumps" occur all the time as a regulating
: mechanism between meals for all healthy people. That is how ordinary
: people keep moving and thinking between meals instead of becoming
: hypoglycemic when the glucose in their blood from the previous meal is
: all used up. Their muscles use their own glycogen stores but the brain
: needs the glycogen stores in the liver (and, I understand, in some
: other organs to a lesser degree). The analogy I use is that the liver
: is like our gas tank, supplying fuel as needed.

You have this correct .
:
: The problem we have as diabetics is that several different flaws can
: cause problems. The signaling pathways may cause the liver to release
: glycogen when it isn't needed, providing excessive blood glucose at
: that moment. Or it may release a needed amount, such as on waking or
: during exercise, but our insulin response is flawed and does not
: transport it properly to our cells. In each case the resulting high
: blood glucose levels are an indicator to us of a problem; the solution
: is less simple because the real problem may be our insulin resistance
: or lack of insulin production rather than the glycogen release.

This isn't exactly correct. As diabetics, T1 or T2, there is really only
one flaw and that is for whatever reason natural Insulin isn't able to
properly transport the glucose that is either eaten or natually released
from the Liver. Diabetics or non-diabetics don't release glucose from
the liver unless it is needed. Something has to trigger that release. Most
times it is triggered from the salivary glands once food touches our
mouth. This is one of the reasons we should always test at 1st bite and
not at the end of the meal. Those who test at the end are only fooling
themselves. Either way, as diabetics our systems are flawed in the
ability to utilize glucose correctly. Thus that is what being Diabetic is
all about. Either not enough insulin production or insulin resistance.

Steve.

I'm afraid, as Gys puts it, we will have to agree to disagree. I see
type 2 as a very complex condition.

Each type 2 diabetic has one or more flaws in their glucose/insulin
system. They may have varying levels of insulin resistance, beta cell
loss, signaling pathway faults for insulin or glycogen release or
both, liver or kidney problems or digestive problems just to name a
few. They may also have other associated or separate medical
conditions. Add a few varied pills and supplements to the mix and then
add varying levels of physical fitness and daily activity.

Given those variables your suggestion on testing limits our knowledge
of what is happening far too much.

Cheers, Alan, T2, Australia.
--
d&e, metformin 2000 mg
Everything in Moderation - Except Laughter.
http://loraldiabetes.blogspot.com (Swine Flu, Diabetes and Good Sense)
http://loraltravel.blogspot.com (North-west to Koumac)
.



Relevant Pages

  • Re: How low is too low?
    ... Or will my liver kick in and dump some sugar ... I normally take 2x500 mg Metformin at midnight; ... high from the glucose. ... liver from excessive glucose dumping and reduces the Insulin Resistance ...
    (alt.support.diabetes)
  • Re: Exactly how does metformin work?
    ... liver responds directly or indirectly to insulin levels, ... But blood glucose levels and inusulin levels are directly related. ... sense is that the liver does measure blood insulin levels directly. ...
    (alt.support.diabetes)
  • Re: Not-so-newby
    ... they don't want to test their glucose 4 or more times ... and it's ALL CARBS that we as diabetics have trouble processing. ... My current Dr is making noises about insulin, ... ah hell both your legs... ...
    (alt.support.diabetes)
  • Re: Not-so-newby
    ... they don't want to test their glucose 4 or more times ... and it's ALL CARBS that we as diabetics have trouble processing. ... My current Dr is making noises about insulin, ... ah hell both your legs... ...
    (alt.support.diabetes)
  • Re: Not-so-newby
    ... they don't want to test their glucose 4 or more times ... and it's ALL CARBS that we as diabetics have trouble processing. ... My current Dr is making noises about insulin, which I definitely | don't want to do. ... ah hell both your legs... ...
    (alt.support.diabetes)

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