Re: Can there be an afternoon liver dump?



x-no-archive: yes

Alan S wrote:

I think gluconeogenesis is only part of it. Whether glycogen is
previously stored as the result of carbohydrate input or
gluconeogenesis of protein, a "liver dump" (use whatever technical
words you wish to substitute, Gys) occurs when stored glycogen, form
any source, in the liver is released as a source of energy between
meals to become blood glucose, rather than the blood glucose being
provided immediately after eating carbohydrates.

What about those of us who've eaten so low carb as to be in ac constant state of glycogen depletion?


In that sense "liver dumps" occur all the time as a regulating
mechanism between meals for all healthy people. That is how ordinary
people keep moving and thinking between meals instead of becoming
hypoglycemic when the glucose in their blood from the previous meal is
all used up. Their muscles use their own glycogen stores but the brain
needs the glycogen stores in the liver (and, I understand, in some
other organs to a lesser degree). The analogy I use is that the liver
is like our gas tank, supplying fuel as needed.

Alan, I don't think the routine, healthy trickle of glucose to fuel activity is a "dump." A dump is a LOAD, noticeable due to a spike, and seems to occur in people who routinely run high. I've never had a liver dump in the years I've been testing. The only exception, perhaps, was when I had two months of very high cortisol levels last year, and tested very high even after a small piece of roast chicken.


The problem we have as diabetics is that several different flaws can
cause problems. The signaling pathways may cause the liver to release
glycogen when it isn't needed, providing excessive blood glucose at
that moment. Or it may release a needed amount, such as on waking or
during exercise, but our insulin response is flawed and does not
transport it properly to our cells. In each case the resulting high
blood glucose levels are an indicator to us of a problem; the solution
is less simple because the real problem may be our insulin resistance
or lack of insulin production rather than the glycogen release.

I really don't care what name it is called; what matters is that the
effect is real and those of us who suffer from it need to recognise it
first before we can find our individual solutions to the problem.

Amen.

Susan
.



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