Insulin Resistance Tied to Hepatitis C Infection
- From: Kurt <kurtwheeling1965@xxxxxxxxxxx>
- Date: Fri, 29 Feb 2008 00:06:32 -0800 (PST)
http://diabetes.org/diabetesnewsarticle.jsp?storyId=17087094&filename=20080227/reuters20080227health00000028reutershealthEDIT.xml
or
http://tinyurl.com/3bh69p
(excerpt)
Insulin Resistance Tied to Hepatitis C Infection
NEW YORK (Reuters Health) - Insulin resistance, a "prediabetic"
abnormality of blood sugar, is a specific feature of chronic hepatitis
C virus (HCV) infection, independent of the severity of HCV or the
presence of other metabolic factors, French investigators report.
HCV infection is now recognized as a system-wide disease, Dr. Rami
Moucari, of Universite Denis Diderot-Paris, and colleagues note in a
report in the journal Gastroenterology. Some previous studies have
linked HCV infection to an increased risk of insulin resistance or
full-blown diabetes.
Insulin is the body's key blood sugar-regulating hormone. Normally,
insulin is secreted to clear glucose (sugar) from the blood and
deposit into cells to use as fuel. Insulin resistance occurs when
cells become desensitized to insulin.
In their study, Moucari's team found that 150 (32.4 percent) of 462
chronic HCV patients who did not have diabetes were insulin resistant.
In this group, insulin resistance was associated with the metabolic
syndrome (a cluster of heart disease and diabetes risk factors), as
well as HCV genotypes 1 and 4, significant liver scarring or
"fibrosis," severe fatty liver disease, and being older than age 40.
.
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