Re: Smoking, Diabetes and Death
- From: Alan S <loralgtweightandcarbs@xxxxxxxxx>
- Date: Sun, 25 Nov 2007 23:56:06 +1100
I thought I posted this in asd first time around, but I seem
to have messed it up and it only appeared in mhd so here it
is again:
Hi All
Time to post this again.
I first posted it a long while back, but we've had a lot of
newbies and I notice smoking is being discussed again.
As an ex-heavily-addicted smoker, I know how hard it was to
give up. So no patronising homilies on just quitting.
Usually, scare stories only provide partial help - but I'll
pass these on anyway. Because I don't want to hear from
anyone, anywhere, claiming that smokes aren't harmful
to a diabetic. Yes, my 96yo father-in-law smokes like a
chimney; that simply means that he's one of the lucky ones,
not that I should too. And he isn't a diabetic.
Do a simple google scholar search on those two words
"smoking+diabetes". This is a small sample of the 51,000+
hits.
Just one small snippet among many:
"Particularly, survival of smokers with diabetes on
hemodialysis is abysmal."
A previous poster, Annette, added a lot more info on the
evil weed in her reply to the original post - you'll find
that at http://tinyurl.com/hdnml
For the sake of those who love you (even if that's only
you), quit. It's tough, you may need help to do it, but do
it.
Cheers, Alan, T2, Australia.
Just a few references:
Cigarette smoking and health. American Thoracic Society
http://ajrccm.atsjournals.org/cgi/content/abstract/153/2/861
Cigarette smoking remains the primary cause of preventable
death and morbidity in the United States.
--------------
Preventing cardiovascular events in patients with diabetes
mellitus.
Abraham WT.
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_...
Smoking is known to be particularly dangerous for those with
diabetes, and it is important for health care providers to
help their patients stop smoking.
-------------------
Effects of smoking on systemic and intrarenal hemodynamics:
influence on renal function.
http://jasn.asnjournals.org/cgi/content/abstract/15/1_suppl/S58
The mechanisms of smoking-induced renal damage are only
partly understood and comprise acute hemodynamic (e.g.,
increase in BP and presumably intraglomerular pressure) and
chronic effects (e.g., endothelial cell dysfunction). Renal
failure per se leads to an increased cardiovascular risk.
The latter is further aggravated by smoking. Particularly,
survival of smokers with diabetes on hemodialysis is
abysmal.
----------------
Effects of cigarette smoking, diabetes, high cholesterol,
and hypertension on all-cause mortality and cardiovascular
disease mortality in Mexican Americans. The San Antonio
Heart Study
http://www.aje.oupjournals.org/cgi/content/abstract/144/11/1058
After adjustment for sex, age, and socioeconomic status in
multivariate analyses, current smoking, diabetes, high
cholesterol, and hypertension were positively associated
with all-cause mortality and cardiovascular disease
mortality in Mexican Americans. Overall, these risk factors
accounted for 45% of all-cause mortality and 55% of
cardiovascular disease mortality in this ethnic group.
----------------
Smoking, diabetes and hyperlipidaemia.
http://rsh.sagepub.com/cgi/content/abstract/118/2/91
Mikhailidis DP, Papadakis JA, Ganotakis ES.
Department of Chemical Pathology & Human Metabolism, Royal
Free Hospital & School of Medicine, Univ. of London, United
Kingdom.
The epidemiological evidence linking smoking with insulin
resistance is considerable. This evidence is even more
convincing because there is a dose response relationship
between smoking and the risk of non-insulin dependent
diabetes (NIDDM). Similarly, there is a time-dependent
decrease in risk of NIDDM for those who quit smoking.
Insulin resistance (in the form of impaired glucose
tolerance, IGT) may precede the development of NIDDM. There
is a biochemical basis for the smoking-IGT/NIDDM
relationship. Smoking increases the risk of developing
diabetic complications like nephropathy, neuropathy and
retinopathy Smoking is also an independent risk factor for
myocardial infarction and all-cause mortality in NIDDM.
Smokers are both insulin resistant and lipid intolerant.
--------------
Smoking and diabetes
D Haire-Joshu, RE Glasgow and TL Tibbs
http://care.diabetesjournals.org/cgi/content/abstract/22/11/1887
There are consistent results from both cross-sectional and
prospective studies showing enhanced risk for micro- and
macrovascular disease, as well as premature mortality from
the combination of smoking and diabetes.
------------------
Smoking is associated with progression of diabetic
nephropathy
http://care.diabetesjournals.org/cgi/content/abstract/17/2/126
RESULTS--Progression of nephropathy was less common in
nonsmokers (11%) than in smokers (53%) and patients who had
quit smoking (33%), P < 0.001. In a stepwise logistic
regression analysis, cigarette pack years, 24-h sodium
excretion, and GHb were independent predictive factors for
the progression of diabetic nephropathy.
-------------------
The Effects of a Smoking Cessation Intervention on 14.5-Year
Mortality
http://www.annals.org/cgi/content/abstract/142/4/233?maxtoshow=&HITS=...
or http://tinyurl.com/66oey
Intervention: The intervention was a 10-week smoking
cessation program that included a strong physician message
and 12 group sessions using behavior modification and
nicotine gum, plus either ipratropium or a placebo inhaler.
Results: At 5 years, 21.7% of special intervention
participants had stopped smoking since study entry compared
with 5.4% of usual care participants. After up to 14.5 years
of follow-up, 731 patients died: 33% of lung cancer, 22% of
cardiovascular disease, 7.8% of respiratory disease other
than cancer, and 2.3% of unknown causes. All-cause mortality
was significantly lower in the special intervention group
than in the usual care group (8.83 per 1000 person-years vs.
10.38 per 1000 person-years; P = 0.03). The hazard ratio for
mortality in the usual care group compared with the special
intervention group was 1.18 (95% CI, 1.02 to 1.37).
Differences in death rates for both lung cancer and
cardiovascular disease were greater when death rates were
analyzed by smoking habit.
-----------------
Getting to Goal in Type 2 Diabetes: Role of Postprandial
Glycemic Control
http://www.medscape.com/viewprogram/3036_pnt
Slide 9. MRFIT: Impact of Diabetes on CVD Mortality
These are data from the Multiple Risk Factor Intervention
Trial (MRFIT) study, where people with and without diabetes
were classified as having: no risk factors at all, only 1
risk factor, 2 risk factors, or all 3 risk factors. Risk
factors were hypertension, hyperlipidemia, and smoking. For
any given number of risk factors, the chances of getting
cardiovascular disease are markedly increased in people with
type 2 diabetes. This increased risk is related to
hyperglycemia.
Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraldiabetes.blogspot.com
Psyllium, Fibre, Muesli and Nuts
.
- Follow-Ups:
- Re: Smoking, Diabetes and Death
- From: Helen Back
- Re: Smoking, Diabetes and Death
- From: Loretta Eisenberg
- Re: Smoking, Diabetes and Death
- Prev by Date: Re: Holy double digits batman!!!!
- Next by Date: Re: Smoking, Diabetes and Death
- Previous by thread: OT: A friend is suffering ...
- Next by thread: Re: Smoking, Diabetes and Death
- Index(es):
Relevant Pages
|
