Re: how amylin works
- From: "Ozgirl" <are_we_there_yet@xxxxxxxxxx>
- Date: Fri, 19 Oct 2007 08:52:10 +1000
"rk" <rksays@xxxxxxxx> wrote in message
"Ozgirl" <are_we_there_yet@xxxxxxxxxx> wrote in message
| "KC" <nomail@xxxxxxxxx> wrote in message
| > "rk" <rksays@xxxxxxxx> wrote in message
| > news:e8ednWc4LJMkA4vanZ2dnUVZ_r-vnZ2d@xxxxxxxxxxxxxxxxxxx
| >> "Jackie Patti" <jpatti@xxxxxxxx> wrote in message
| >> news:47166400$0$7203$470ef3ce@xxxxxxxxxxxxxx
| >> | KC wrote:
| >> |
| >> | The reason I didn't solve this to my own satisfaction was that T2s
| >> | fat and T1s do not. I realize this is a generalized statement, but
| >> | is a generally observed phenomenon that has to be explained when
| >> | understanding these hormones. I can't come up with a theory that
| >> covers
| >> | this fact and explains glucose metabolism with only the 3 hormones
| >> being
| >> | significant.
| >> |
| >> | I suspect the difference as per fat metabolism is related to the
| >> unknown
| >> | I postulate that explains both insulin resistance and amylin
| >> resistance.
| >> | When we know this, we'll know how glucose really works.
| >> |
| >> little bit of info as to an average T1 (what my doctor thinks I am)
| >> 3-4
| >> months prior to diagnosis, I started to eat like an utter pig.
| >> these
| >> facts with my medical reports at home) I didn't gain much, about
| >> was all, but it did happen within a short time. I attributed it to
| >> sitting
| >> on my
| >> arse and sleeping almost immedately after meals. a few weeks later,
| >> began
| >> to drop weight like crazy and lost 47lbs in 7 weeks. I found out my
| >> weight
| >> loss when I was in the ER.
| >> the point is this.. the cause for increased weight with diabetics is
| >> increased
| >> insulin production. insulin is a growth hormone and is for fat
| >> so
| >> with
| >> increased insulin, there is naturally going to be increased body fat
| >> (weight). I
| >> know even now, that if I eat too much and don't exercise right then
| >> gain
| >> weight. it's not like being a T1 is a guarantee to keep thin, though
| >> does help.
| >> if I gain a bit of weight, I'll often welcome a cold or flu, because
| >> can't eat and
| >> often will have ketones (just from the illness) which causes me to
| >> weight.
| >> never recommended! but there have been times, I've been out (prior to
| >> pumping)
| >> and we've stopped to eat and I've not injected until we get home,
| >> during
| >> a few hours, I get enough increase in glucose to cause ketones and
| >> nice 1-2
| >> lbs weight loss for me without trying.
| > Interesting as I thought the ketones were from the lack of insulin to
| > point that the body starts using fat from not being able to use
| > not from the blood sugar going high. I would have thought that your
| > insulin would keep you from getting ketones even if your blood sugar
| > high.
| Ketones are a by-product of burning fat - dietary ketosis. It takes
| days without carbs before ketones present in the urine. So #1, Reisa's
| ketosis wouldn't be dietary unless she had been on a strict low carb
| for longer than 3 days.
| Ketoacidosis (what type 1's get when insulin is low and sugar is high)
| be very rare from only missing one bolus shot. The weight loss
| with DKA is from dehydration.
I guess you forget that I pump. I don't have a "long acting" insulin in
I get for a bolus is mostly gone within a few hours.
I guess you forgot that this part of the conversation came out of this
comment of yours:
"but there have been times, I've been out (prior to
|pumping) and we've stopped to eat and I've not injected until we get home,
which during a few hours, I get enough increase in glucose to cause ketones
and it's a nice 1-2 lbs weight loss for me without trying."
As ketones are formed from burning of fat, there is no way you could burn
1-2 pounds of fat in a small few hours of missing an insulin shot. Once
again, if there was any weight loss it would be from dehydration. Once again
high glucose does not cause ketones directly. Lack of insulin is the key and
it prevents glucose getting into the cells which causes the glucose to
remain in the blood. The cells are starved by not getting the glucose they
need so they will need to use fat as energy. That is when ketones are
formed - the by-product of fat burning. For one meal, 1-2 pounds of fat
could not physically be burnt.
The scenario you spoke about, whilst no doubt an accident on your part, is a
dangerous practice if deliberate. You really shouldn't have tacked on this
bit "and it's a nice 1-2 lbs weight loss for me without trying." That
doesn't send a good message to anyone who might be lurking, who may have a
body image problem and be a type 1.
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