Re: Low glycemic load diet improves acne in young men


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Low-Glycemic-Load Diet May Improve Acne in Young Men CME

Release Date: July 27, 2007; Valid for credit through July 27, 2008

July 27, 2007 ? A low-glycemic-load diet reduced acne lesions in male
patients aged 15 to 25 years, according to the results of a randomized
controlled trial study published in the July issue of the American Journal
of Clinical Nutrition.

"Although the pathogenesis of acne is currently unknown, recent
epidemiologic studies of non-Westernized populations suggest that dietary
factors, including the glycemic load, may be involved," write Robyn N.
Smith, MD, from RMIT University in Melbourne, Australia, and colleagues.
"Recently, there has been a reappraisal of the diet and acne connection
because of a greater understanding of how diet may affect endocrine
factors involved in acne.... Hyperinsulinemia has been implicated in acne
pathophysiology because of its association with increased androgen
bioavailability and free concentrations of insulin-like growth factor I
(IGF-I)."

In this 12-week, parallel design, investigator-blinded study, 43 male acne
patients aged 15 to 25 years were randomized to receive a
low-glycemic-load diet (25% energy from protein and 45% from
low-glycemic-index carbohydrates) or a control diet rich in
carbohydrate-dense foods without consideration of the glycemic index.
Outcome measures included monthly dermatologic evaluation of acne lesion
counts and severity. Using the homeostasis model assessment, insulin
sensitivity was determined at baseline and at 12 weeks.

Mean reduction in total acne lesion counts at 12 weeks was -23.5 ± 3.9 in
the low-glycemic-load group and -12.0 ± 3.5 in the control group (P =
.03). Compared with the control diet, the low-glycemic-load diet was also
associated with a greater decrease in weight (-2.9 ± 0.8 vs +0.5 ± 0.3 kg;
P < .001) and body mass index (-0.92 ± 0.25 vs +0.01 ± 0.11 kg/m2; P <
.001) and a greater improvement in insulin sensitivity (-0.22 ± 0.12 vs
+0.47 ± 0.31; P = .026).

Study limitations include the possibility that topical application of a
mild skin cleanser may have contributed to acne improvement; inability to
rule out the effect of other dietary factors, such as zinc and vitamin A
intake, on acne improvement; and reliance on self reporting of dietary
intakes.

"The improvement in acne and insulin sensitivity after a low-glycemic-load
diet suggests that nutrition-related lifestyle factors may play a role in
the pathogenesis of acne," the authors write. "However, further studies
are needed to isolate the independent effects of weight loss and dietary
intervention and to further elucidate the underlying pathophysiologic
mechanisms."

Meat and Livestock Australia supported this study.

Am J Clin Nutr. 2007;86:107-115.

Of course I'm not young or a man, but... What helped me was stopping milk.
My parents used to make me drink it three times a day. When the Dr. told
them to stop giving me milk, my face cleared up almost immediately.


.

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