Re: Type 2 Diabetes


"hlmw" <hlmw1@xxxxxxxxx> wrote in message news:Yv39i.534$kY6.279@xxxxxxxxxxx
Ozgirl wrote:
Defining type 2.

http://www.diabetes.org/type-2-diabetes.jsp :

"Type 2 diabetes is the most common form of diabetes. In type 2
diabetes,
either the body does not produce enough insulin or the cells ignore the
insulin. Insulin is necessary for the body to be able to use sugar."

Simple explanation but a start.

http://www.medscape.com/viewarticle/492723_1 :

"As insulin resistance increases, it is now appreciated that the beta
cell
compensates by producing more insulin -- but at a cost to the beta cell.
For
a number of reasons, beta-cell apoptosis, or early cell death, occurs,
which
results in relative insulin deficiency and eventually hyperglycemia to
the
level of diagnosis of diabetes."

Note that the insulin deficiency comes "before" hyperglycemia has
reached a
level where one is officially diagnosed.


http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=15
132880&dopt=Abstract :

"Joslin Diabetes Center, One Joslin Place, Room 346, Boston, MA 02215,
USA.

Type 2 diabetes is the result of a progressive impairment of pancreatic
beta-cell function in the setting of worsening insulin resistance.
Studies
in high-risk populations have demonstrated that during progression to
diabetes, beta cells have declining function and lose the first phase of
insulin secretion, resulting in less than adequate suppression of
hepatic
glucose production following meals."

Why are people diagnosed at the hyperglycemic level rather than the low
- dumb question?

Because the powers that be say so. It's one of my big bug-bears! To me, it
makes sense to treat a person before they start showing complications and
beta cell loss.

.

Relevant Pages

  • Re: Researchers Discover Mechanistic Link Between High-Fat Diet and Type 2 Diabetes
    ... > insulin production, resulting in the classic signs of type 2 diabetes. ... > failure of the pancreatic beta cells. ... > GnT-4a, said the researchers. ...
    (sci.med.nutrition)
  • Re: One In Four In Americans Has Diabetes? Taking Insulin For Type II Is Making Things Worse?
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    (alt.support.diabetes)
  • Re: Age at Diagnosis
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    (alt.support.diabetes)
  • Re: Anybody had luck with a High Carb Plant based diet
    ... Here for example is an article "Advances in Diabetes for the ... Understanding Insulin Resistance" from Medscape's ... The UKPDS data indicate at diagnosis that patients with type 2 ... half your beta cells and still have enough for normal daily BG ...
    (alt.support.diabetes)
  • Salacia Oblonga For Diabetes
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