Re: MUFA diet for T2D

On May 2, 5:44 pm, "GysdeJongh" <jongh...@xxxxxxxxx> wrote:
The conclusion is that the effect of the diet can be seen ONLY in T2D , not
in obese but non diabetic patients.This seems to disappoint the authors.I
personally find it encouraging.I think T2D is characterized by a metabolic
defect in fat/carbohydrate.Very nice if the defect can be circumvented by
MUFA : Salmon , Olive Oil ........

"However, fasting blood glucose and HbA(1c) decreased (P < 0.01) and
high-density lipoprotein cholesterol increased significantly only in the
T2D/Mufa group (P < 0.05) "

Diabet Med. 2007 May;24(5):533-40. Epub 2007 Mar 22.

A comparison of the influence of a high-fat diet enriched in monounsaturated
fatty acids and conventional diet on weight loss and metabolic parameters in
obese non-diabetic and Type 2 diabetic patients.

Aims The aim of our study was to compare the influence of a hypocaloric,
high-fat diet enriched with MUFA (M) and conventional diet (C) on weight
loss and metabolic parameters in obese non-diabetic and obese Type 2
diabetic subjects over a 3-month period. It was our hypothesis that the
enriched diet would be more effective in decreasing blood glucose and
glycated haemoglobin (HbA(1c)) than the control diet. Methods Twenty-seven
Type 2 diabetic patients (54.5 +/- 3.5 years; DM), treated with diet or oral
glucose-lowering agents, and 31 obese non-diabetic subjects (53.6 +/- 3.5
years; OB) were randomized to M or C. Individual calculations of energy
requirements were based on the formula: [resting energy expenditure (REE) x
1.5] - 600 kcal. Subjects were assessed by a dietitian every 2 weeks and by
a physician every month. Statistical analyses were carried out between the
four groups-DM/M, DM/C, OB/M and OB/C-using pair Student's test and anova.
Results After 3 months, body weight, waist-hip ratio, total body fat, levels
of C-peptide, triglycerides and homeostasis model assessment (HOMA)
decreased in all four groups (P < 0.01). However, fasting blood glucose and
HbA(1c) decreased (P < 0.01) and high-density lipoprotein cholesterol
increased significantly only in the DM/M group (P < 0.05). In general, M was
well tolerated. Conclusions Individualized M and C diets were successful in
improving metabolic and anthropometric parameters in both the obese
non-diabetic and the Type 2 diabetic subjects. Although the superiority of
the higher fat diet did not reach statistical significance, the decline in
blood glucose and HbA(1c) in the Type 2 diabetic group on M was encouraging.

PMID: 17381504

hth
Gys

Thanks for posting this interesting study. The fact that the diet
worked better for T2s demonstrates--once again--that people are all
different; that what works for one group of people may not have the
same effect in another group.

I have always been a bit baffled about why the American Heart
Association and other health organizations put out dietary guidelines
assuming that what is healthy for some will be healthy for others.
I'm sure everyone can agree that we all need our vegetables, but I
made my reactive hypoglycemia worse (many years back) by following the
American Heart Association diet which promotes getting a significant
amount of calorie from carbs (50-60%). This diet may be fine, and
even helpful, for those who are not susceptible to diabetes, but it
was definitely not good for me.

By the way, I see that you mentioned you are not a native speaker....I
must say that you express yourself in English very well. I'm quite
impressed--and a little envious. I am currently learning Spanish, and
let's just say I have a long way to go. ;-)

Best regards,
Michelle C., T2
diet & exercise

.

Relevant Pages