Re: Timescale in which newbies should get control
- From: Chris J. <chris@xxxxxxxxxxxx>
- Date: Wed, 01 Mar 2006 11:01:38 -0700
On Tue, 28 Feb 2006 09:01:01 -0500, Jenny <lottadata@xxxxxxxxxxx>
wrote:
Chris J. wrote:
If my HOMA analysis of my C-peptide/FBG ratio is accurate, I only have
60% insulin sensitivity, so have a 40% deficiency (as of 3 months
after Dx). On the other hand, my BG profile and carb response lately
is more similar to IGT: brief spikes, more of a delayed rather than a
deficient pancreatic response.
I would not give that C-peptide/FBG ratio much credence. In my case, the
result it gave did not correspond at all to the measure of insulin
sensitivity provided by how my body responds to 1 unit of R insulin.
Mine is suspect for another reason: one side of the equation gave
preposterous results. It claimed I had 137% pancreatic capacity!
I've been thinking of trying the one unit of R test, but not while
this IGF-1 issue is still unresolved. Also, how would I do it? I'm
assuming that I'd want to try it on stable between meal BG's, but
those run in the upper 70's if I'm not eating, and I wouldn't want to
lower them below that (and my liver might interfere if I tried).
My problem here is that my BG's, when not at their stability range
(80, plus or minus 5) are exceedingly volatile; they change very
quickly.
Your brief bout of severe diabetes seems very likely to have been a
response to the infection. Is it possible that a bunch of your beta
cells shut down for a couple days due to some chemical imbalance caused
by the severe infection?
That's quite possible. Or, the infection sent my IR through the roof
(as infections are well known to do).
This brings up another interesting theory: If insulin is to blame,
including that I produce myself, then still having most of my
pancreatic function could have been causal for my normoglycemic
re-entry phenomenon.
If that is the case, it may have turned out that even without the
insulin your blood sugars would d have dropped down swiftly from
extremely high back to near normal on their own (possibly permanently a
bit worse due to glucose toxicity wiping out beta cells),
I am not sure on that. I did have symptoms of diabetes (tiredness,
etc.) for over a year pre Dx, and I suspect that I had high BG's long
before the infection (and they could have caused the infection). I
also have one test showing sugar in my urine from 20 years ago.
One interesting coincidence: some forms of rice (mainly, when rice is
used as an ingredient) spike me far more than anything else, vastly
more than pure sugar. This is interesting because I made some dietary
changes a year before Dx: I went from being a very rare rice eater to
being a frequent one.
You might also want to take a look into the research on the effects of
temporary but very high blood sugars caused by severe infection or
cortisone which resolve after the crisis and whether they too have been
associated with your kind of problem.
That's a good idea! I'll do that. Thanks!
.
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