Re: Why not Insulin for everyone?
- From: "Anon" <anon4592004@xxxxxxxxx>
- Date: Tue, 27 Dec 2005 22:51:24 -0800
I downloaded the risk engine. The results are quite depressing. If what they
say is true I better get my will in order.
Using the numbers from my most recent labs, I have a 10.5% chance of fatal
heart attack during the next 10 years. If I plug in my most optimistic
improvements, the risk is still 10%.
"oldal4865" <oldal4865@xxxxxxxxx> wrote in message
news:41ec25F1ee111U1@xxxxxxxxxxxxxxxxx
>
> Nirvana wrote in message ...
>>Hey
>>
>>Still having problems with my bg being too high, especially in the
>>morning.
>>No matter what I do it keeps rising until about 10 am.
>>I have tried low carbs in the morning, high carbs in the morning, no carbs
>>in the morning. high carb snack before bed, low carb snack before bed, no
>>snack before bed. My latest bright idea, that does not work was to get up
> at
>>4 am and eat breakfast.
>>
>>Several of you have suggested that I might need to be on insulin. I see my
>>doc on Fri.
>>
>>
>>Actually, I hope she puts me on insulin it sounds better that taking tons
>>for meds and not getting results.
>>
>>
>>So, Is there a reason that docs don't put T2s on insulin instead of meds?
>>I
>>here it is cheaper and sound like it works better.
>>
>>
>>
>>Still just trying to figure this disease out
>>
>>
>>Nirvana
>>
>>34 year old male
>>5'8 170 lbs.
>>T2
>>Metformin (1000mg) dinner
>>Glyburide (10mg) breakfast and dinner
>>Prandin (3mg) breakfast, (1mg) lunch and dinner
>>
>>
>
> 1. Insulin INSTEAD of meds for T2:
>
> If you are T2 then, statistically, your #1 problem is a high risk
> of
> Premature Heart Attack due to high Insulin Resistance.
>
> Insulin does a fine job of bG control for T2 but not much else**. T2
> must address their (statistical high probability of) high Insulin
> Resistance.
>
> Metformin is a fine anti-Insulin Resistance med. Note that the U.S. PDR
> asserts that the usual maintenance dose is 1500 - 2550 mg/day.
>
> http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/glu1188.shtml
>
> The rest of the anti-Premature Heart Attack equation is:
>
> a. Lose fat lb.
> b. Gain muscle lb.
> c. Exercise every day
> d. Eat low carb
>
> (Yes, eating low carb helps with bG control but for a high Insulin
> Resistant T2, it also helps with premature heart attack risk.
> For many T2, high carb equates to high triglycerides levels. High
> triglycerides levels equate to high premature heart attack risk. )
>
> If T2 go on insulin-only as their sole therapy, they can achieve superior
> bG control but are likely to also achieve sky-high triglycerides and thus
> sky-high risk of premature death. Insulin is a great idea for T2 but
> anti-Insulin Resistance comes first.
>
> Not all T2 have high Insulin Resistance. Check your non-medicated
> triglycerides/HDL ratio. A ratio of 3 or more means high Insulin
> Resistance. A HOMA analysis is as good or better. Maybe you can have
> your doc measure both. See HOMA at:
>
> http://www.dtu.ox.ac.uk/index.html?maindoc=/riskengine/
>
> I would be fascinated with your HOMA scores. A recently diagnosed
> adult-onset diabetic with a BMI of 26 experiencing bG problems despite two
> beta stimulators and metformin really sounds like adult-onset T1.
>
> (**High bG also contribute to premature heart attack risk. Anything
> which
> knocks down bG will thus have some sort of anti-Heart attack effect. My
> interpretation of the medical sites is that high I.R. produces the greater
> premature heart attack risk )
>
> 2. Insulin AND meds for T2:
>
> Glyburide and Prandin are beta stimulators which force your dying beta
> cells to put out more insulin. Many folks think that over-working the
> beta cells increases their death rate and thus accelerates the arrival of
> the day on which your betas don't do any good at all. . . ahem. . .like
> mine.
>
> You won't like that. Would you like a detailed explanation based on the
> PITA I go through every day, or would you please take my word that you
> won't like that?
>
> Of course, using early insulin as a -- supplement -- to protect T2***
> beta cells (after doing something to knock down your Insulin Resistance)
> is
> much preferable than the down-the-road PITA insulin regime which
> accompanies
> mostly dead beta cells. It's sort of "Pay me now or pay me later" with
> Pay me now being much cheaper.
>
> (***Early insulin doesn't do much to protect dying T1 beta cells)
>
> IMO, insulin is a better choice than Glyburide and/or Prandin unless you
> have physical impairments which make the convenience of the pills more
> important than the risk of accelerated beta cell death. Insulin therapy
> is much more powerful and much more controllable than the pills.
>
> Regards
> Old Al
>
>
>
.
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