Re: My longest winded post to date - SUBJECT: OBESITY VS DM


CeeBee wrote:
> rleone@xxxxxxxxxxx wrote in alt.support.diabetes:
>
> > I think I'll go with the more nuanced, subtle, complex idea there's
> > a "thrity gene" out there, and oh yeah, in me, that is related to both
> > developing diabetes and being obese in an interrelated way.
>
>
> An obesity gene isn't a gene that makes you obese, but a genetic disposition
> that make you store your body fat in a way much more efficient than other
> people. There might be clues that the workings of this "obesity gene" works
> the same way as the genetic disposition that puts you at greater risk of
> getting T2 diabetes.
SNIPPING (of cogent, absolutely spot-on material, not dismissing it).

Sorry CeeBee -- bad spelling on my part. I meant "thrifty gene," not
"obesity gene." It's GREAT to have in a hunter-gatherer or subsistance
agrarian economy that is subject to famine, because you sock on the fat
in times of relative plenty and don't die as easily of starvation in
times of want. However, with times of not just plenty but positivie
overabundance just a hop, skip and drive away at the quickie market,
palace di deep fried fat or whatever, and relative market insulation
from food underproduction (thank you global economy), the ol' thrifty
gene becomes, er, maladaptive. At least that's the theory as I've come
across it.

Thank you for the correction. I deeply appreciate it.

Robert Leone rleone@xxxxxxxxxxx

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