Re: LAB tests reply

Priscilla H. Ballou wrote:
> In article <1123566566.897530.171210@xxxxxxxxxxxxxxxxxxxxxxxxxxxx>,
> "just Ed" <just_ed53spam@xxxxxxxxx> wrote:
>
> > Somebody in the thread suggested pantethine.
> > pantethine is a statin.
>
> I had understood "statin" to be a class of prescription pharmaceutical.
> Is there a broader definition of it? I've been avoiding prescribed
> statins due to their side effects, but I take pantethine because I'd
> understood it to not have those same side effects. Now I feel confused.
>
> Priscilla

plenty of definitions are out there on the web based on what these
chemicals do.
search 'statin definition':
statin = HMG reductase inhibitor
(the rate limiting enzyme in cho production)

some definitions out there are so broad that they include almost
all ways of dropping cho, I don't think those are useful definitions.

pantethine inhibits the same enzyme as the pharma statins, it
does the same thing.

pantethine is pretty mild.
I don't know of any side effects reports.

The key to side effects is whether is can inhibit that enzyme
completely enough to cause a problem (like low CoQ10) or
mess with all the isoprenoid chemistry or whatever else causes
the bad effects. That's not well understood.

I mainly didn't want the OP to start pantethine on top of her
crestor after pantethine was mentioned to her, and I'd suggest
the same caution to you or anyone who is on a pharma statin.
(I think that the other Susan agrees and didn't intend the OP
to take that as a suggestion.)

There may be something which would limit the additive effects of
taking pantethine with another statin, but I wouldn't gamble my
health on that without lots of data on what's going on (or if
my LDL were sky high).

Ed

.

Relevant Pages

  • Re: One more safe alternative to statins
    ... "pantethine is known to be well tolerated" no bias here!!!! ... 6442152 rabbit study irrelevant to human tolerability, ... to possibly start to compare to statin data doesn't state duration ... I would not accept your claims for safety and efficacy of a statin ...
    (sci.med.cardiology)
  • Re: One more safe alternative to statins
    ... >> 5 6442152 rabbit study irrelevant to human tolerability, ... >> to possibly start to compare to statin data doesn't state duration ... >> your claims for pantethine having been proven safer than statins, ...
    (sci.med.cardiology)
  • Re: One more safe alternative to statins
    ... "pantethine is known to be well tolerated" no bias here!!!! ... 6442152 rabbit study irrelevant to human tolerability, ... LDL changes not significant ... to possibly start to compare to statin data doesn't state duration and its weak comment on "very good tolerability" could mean that only 6 of 1045 had severe reactions. ...
    (sci.med.cardiology)
  • Re: LAB tests reply
    ... >> Somebody in the thread suggested pantethine. ... > I had understood "statin" to be a class of prescription pharmaceutical. ...
    (alt.support.diabetes)
  • FDA rejects OTC statin
    ... to gain approval for nonprescription sales of Mevacor. ... The drug is a part of the widely used class of prescription ... Merck's third bid to sell the cholesterol-lowering drug without a ... Mevacor is one of the statin drugs taken by millions to cut ...
    (sci.med.cardiology)