The Ticking-Clock Hypothesis?
- From: "Larry" <boelkowj@xxxxxxx>
- Date: 4 Aug 2005 08:54:25 -0700
I just read carefully one of the San Diego ADA papers presented in June
2005. A good paper (Natural History of the Metabolic Syndrome and Type
2 Diabetes: The Ticking Clock) but could be misinterpreted as the focus
was primarily the natural history of Metabolic Syndrome leading to full
blown T2 Diabetes. Dr.Aaron Vinik did refer to one study ie. European
Prospective Investigation of Cancer and Nutrition/Norfolk cohort where
it states "..every 1.0% increase in A1C was associated with a 28%
increase in the risk of death, independent of age, blood pressure,
serum cholesterol, body mass index, or cigarette smoking habit".On the
whole Dr.Vinik's reviewed new "tools" to treat Diabetes that should
become available in the next couple years but unfortunately generalized
to the extreme case by focusing on the mortality of those diabetics who
start out with Metabolic Syndrome(ie.
hypertension,overweight,dyslypidemia)before developing Diabetes. What
about more information on study results for those diabetics who never
develope hypertension or obesity? I am suggesting that Dr.Vinik's paper
could be easily misunderstood since the independent co-morbidities of
obesity, hypertension, dyslipidemias were not clearly delineated and
lumped together under complications of Diabetes. His concluding comment
was "We need to learn how to modify behavior in order to make a big
dent in the incidence of macro- and microvascular complications of
diabetes. My problem is that I can lead a horse to water, but I have
not yet learned how to make it drink." (Does he have an attitude?) I
believe his comments showed his "agenda" and a slant in profiling the
normal history of T2 Diabetes to the more complicated class of Type 2
Diabetes.
Larry
.
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