Re: FDA crawls from under rock- Claims Neurontin dangers
- From: "Ray" <raydarx@xxxxxxxxxxx>
- Date: Sun, 3 Feb 2008 07:37:40 -0600
Thanks OG
I'm always interested in the so called migraine preventative use of epilepsy
medications. They pushed Topanx and Neurontin
on me at the same time and I had horrible side effects. Including word
finding problems and slurring out words that don't exist in my language. It
was my friends who picked up on how much of a change in my personality they
were causing, although I knew there was a drastic drop in IQ. And I'm
convinced the Topamax has caused permanent damage as it's been over a year
ago.
The Neurologic Clinic, Department of Medical and Surgical Specialties and
Public Health, University of Perugia, Italy did a study and there
Conclusion.- It can be hypothesized that a disorder such as migraine, which
involves numerous cortical and subcortical circuits implicated in the
transmission and behavioral and emotional processing of pain, represents a
facilitated substrate for the occurrence of language disturbances due to
topiramate. This could be the expression of a more generalized impairment of
cognitive processing. These aspects should be investigated in prospective
studies involving larger migraine patient samples.
There are a boat load of migrainers that say it helps them a lot and for
some I'm sure it's a life saver, but there are also many who have had to
stop because of the side effects and one of them is turning there brain to
mush. And there are a lot of doctors that don't seem to think it's even
worth mentioning to the patient before they perscripe it to them or even
when it is reported back to them they tend not be to concerned about it, in
my case anyway. If it was them that were having the same problems they
wouldn't be able to function at there job.
My appointment in January with my new neroligest that I have seen 4 times
now didn't go over so well. They lost my file and the paper I usally bring
in with questions and so forth because I have such a bad memory.....I forgot
to bring it. Duh!
We disgused lowering my dose with two medcations and that was fine by me.
Then when he contacted my doctor at home here and I went in for the
appointment he said the neurologist wants to cut back on ALL my medications
and prescribed another medication - Lamotrigine. Another anti-seizure Med!
In my file the drugs Topamax and Neurontin had a star next to them
indicating I can't tolerate those meds well.
So here we go again with the B.S.
"OldGoat" <oldgoatmail@xxxxxxxxxxxxxxxxxx> wrote in message
news:kswoj.11106$O9.10897@xxxxxxxxxxx
FDA warns of risks from epilepsy drugs
2 hours, 21 minutes ago
Epilepsy drugs used by millions of people may increase the risk of
suicidal thoughts or behavior, the Food and Drug Administration warned
Thursday in an alert to doctors.
The FDA analyzed almost 200 studies of 11 anti-seizure drugs, some that
have been on the market for decades. The studies tracked almost 28,000
people given the medications and another 16,000 given dummy pills.
Very rarely were suicidal thoughts or behavior reported. Still, the FDA
found drug-treated patients did face about twice the risk: 0.43 percent of
drug-treated patients experienced suicidal thoughts or behavior, compared
with 0.22 percent of placebo-takers.
Overall, four people in the drug-treated groups committed suicide, and
none in the placebo groups.
What that means: For every 1,000 patients, about two more drug-treated
patients experienced suicidal thoughts than placebo-takers, FDA concluded.
Anti-seizure drugs are used for a variety of illnesses in addition to
epilepsy, including migraines, certain nerve-pain disorders, and
psychiatric diseases such as bipolar disorder that themselves carry a risk
of suicide.
The FDA found drug-treated patients were at increased risk no matter their
diagnosis, but that the risk was highest for epilepsy sufferers.
The FDA began investigating if epilepsy drugs pose any suicide risk in
2005. It analyzed data from 11 well-known anti-seizure drugs including
Pfizer Inc.'s Neurontin, Novartis AG's Tegretol and Abbott Laboratories'
Depakote - but the FDA said it expected the risk applied to every epilepsy
drug. The FDA said it would work with manufacturers to add the warning to
product labels.
Skipping epilepsy medication can result in seizures. An FDA spokeswoman
said only that patients should ask a doctor before making medication
changes.
But the agency's letter to doctors advised them to:
_Balance the risk with the patients' need for the drug.
_Tell patients and their families about the risk so they can be aware of
changes in mood.
_Make sure patients and families know to contact a doctor if someone
experiences common suicide warning signs, such as talking or thinking
about hurting yourself, becoming preoccupied with death, withdrawal,
becoming depressed or worsening depression, and giving away prized
possessions.
--
Be Sure to Check Out the PAYNE HERTZ blog, for people with chronic pain,
by people with chronic pain.
join in at: http://paynehertz.blogspot.com
.
- References:
- FDA crawls from under rock- Claims Neurontin dangers
- From: OldGoat
- FDA crawls from under rock- Claims Neurontin dangers
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