Re: Results of my new doctor search
- From: Zombywoof <Zomby-Woof_dogs_@xxxxxxx>
- Date: Sat, 07 Jan 2006 18:14:22 -0500
On Sat, 7 Jan 2006 15:56:33 -0500, "Rosemarie Shiver"
<post147@xxxxxxxxxx> wrote:
<snip>
>Rx'd legit. Marinol for headaches? Marinol and MJ have headaches as a side
>effect, ya maroon!
>
Cannabis, or marijuana, has been used for centuries for both
symptomatic and prophylactic treatment of migraine. It was highly
esteemed as a headache remedy by the most prominent physicians of the
age between 1874 and 1942, remaining part of the Western pharmacopoeia
for this indication even into the mid twentieth century. Current
ethnobotanical and anecdotal references continue to refer to its
efficacy for this malady, while biochemical studies of THC and
anandamide have provided a scientific basis for such treatment.
Dr. Ethan Russo, University of Montana had several layers of approval
(to include the FDA) for a study titled Cannabis in Acute Migraine
Treatment. The FDA approved the study of the effects of smoked
cannabis (marijuana) as compared to oral dronabinol (Marinol®) and
injected sumatriptan. The study would have enrolled 40 patients with
severe migraine. However, the NIH refused to supply him with the
required Marijuana which they grow at the University of Mississippi
supposedly for research purposes. The sad truth is that NIDA is still
successfully blocking medical marijuana research. The National
Institute on Drug Abuse (NIDA) holds a monopoly on the domestic
supply. They have previously required that any study employing
cannabis must obtain approval and funding through a National Institute
of Health grant.
What cannabis does to alleviate migraines is complicated and not
completely understood. "But it works on serotonin and dopamine
receptors, and has anti-inflammatory activity," says Russo, who is
just finishing a paper for the Journal of Cannabis Therapeutics.
"Basically, it is a multi-modality agent that works on various aspects
of migraine in a way that's really unique. And it's not just the THC ?
tetrahydrocannabinol, the psychoactive chemical ? that does it. It
appears now that it's the result of the interaction of a combination
of other cannabinoids and also the essential oils in the plant."
Unlike most headache medications, cannabis is unique in that it works
as both a preventive agent and an analgesic. "At any point in the
migraine, they could use cannabis by smoking, vaporizer, etc., and
about 80% of these people get significant or total relief," he says.
"And, if someone has a chronic migraine, daily use in whatever form
will often lead to a complete remission."
Bureaucratic Impediments:
The cannabis mechanism is not fully understood because there hasn't
been enough research. Despite all the claims of its beneficial effect
on migraines, there has yet to be a scientific study investigating the
therapeutic use of marijuana for migraines.
Other references:
http://www.medmjscience.org/Pages/history/russo.bhtml
http://www.idmu.co.uk/cannmigraine.htm
http://www.druglibrary.org/schaffer/hemp/migrn1.htm
--
"Everything in excess! To enjoy the flavor of life, take big bites.
Moderation is for monks."
ZombyWoof
(take the dogs when replying via e-mail)
.
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