Re: Fibromyalgia - a disorder of the brain?


<Sampatron@xxxxxxx> wrote in message news:d5c70114-174a-4140-a6e1-f5c4600f7214@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
On Feb 20, 4:47�pm, "Cheeky ***" <InvalidEm...@xxxxxxx> wrote:
AKA they are back to claiming "it's all in your head".

<Sampat...@xxxxxxx> wrote in message

news:01a24126-48c4-4e7a-9469-8b3139a77c4c@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx



> On Feb 20, 2:10 pm, Strandkruier <Strandkru...@xxxxxxxxx> wrote:
>> Hi, folks,

>> Some professional here who might provide me with this article:
>> Petra Schweinhardt, Khara M. Sauro, and M. Catherine Bushnell
>> � � Fibromyalgia: A Disorder of the Brain?
>> � � Neuroscientist first published on February 12, 2008 as
>> doi:10.1177/1073858407312521 ?
>> (For personal use only)

>> Thank you in advance

>> Norbert (from Flanders, Belgium)
>> Please, send to: strandkru...@xxxxxxxxx

> It'll cost to get the entire article unless you have a subscription to
> Neuroscientist. �However, here's the abstract and contact person if
> that will help:

> First published on February 12, 2008
> The Neuroscientist 2008, doi:10.1177/1073858407312521
> (c) 2008 SAGE Publications

> ---------------------------------------------------------------------------�-----

> Article

> Fibromyalgia: A Disorder of the Brain?
> Petra Schweinhardt, Khara M. Sauro, and M. Catherine Bushnell, Ph.D.*
> Center for Research on Pain, McGill University

> * To whom correspondence should be addressed. E-mail:
> catherine.bushn...@xxxxxxxxxx

> � Abstract
> This article presents evidence that fibromyalgia patients have
> alterations in CNS anatomy, physiology, and chemistry that potentially
> contribute to the symptoms experienced by these patients. There is
> substantial psychophysical evidence that fibromyalgia patients
> perceive pain and other noxious stimuli differently than healthy
> individuals and that normal pain modulatory systems, such as diffuse
> noxious inhibitory control mechanisms, are compromised in
> fibromyalgia. Furthermore, functional brain imaging studies revealing
> enhanced pain-related activations corroborate the patients' reports of
> increased pain. Neurotransmitter studies show that fibromyalgia
> patients have abnormalities in dopaminergic, opioidergic, and
> serotoninergic systems. Finally, studies of brain anatomy show
> structural differences between the brains of fibromyalgia patients and
> healthy individuals. The cerebral alterations offer a compelling
> explanation for the multiple symptoms of fibromyalgia, including
> widespread pain and affective disturbances. The frequent comorbidity
> of fibromyalgia with stress-related disorders, such as chronic
> fatigue, posttraumatic stress disorder, irritable bowel syndrome, and
> depression, as well as the similarity of many CNS abnormalities,
> suggests at least a partial common substrate for these disorders.
> Despite the numerous cerebral alterations, fibromyalgia might not be a
> primary disorder of the brain but may be a consequence of early life
> stress or prolonged or severe stress, affecting brain modulatory
> circuitry of pain and emotions in genetically susceptible individuals.
> NEUROSCIENTIST XX(X):xx-xx, XXXX. DOI: 10.1177/1073858407312521- Hide > quoted text -

- Show quoted text -



Yeah, but this time it's a whole 'nother smoke! *G*

Blissings,
Sam

Yeah and it's being blown upwards... <g>

CB

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