Re: Fibromyalgia - a disorder of the brain?

On Feb 20, 4:12�pm, Strandkruier <Strandkru...@xxxxxxxxx> wrote:
On Wed, 20 Feb 2008 13:34:39 -0800 (PST), Sampat...@xxxxxxx wrote:
On Feb 20, 2:10 pm, Strandkruier <Strandkru...@xxxxxxxxx> wrote:
Hi, folks,

Some professional here who might provide me with this article:
Petra Schweinhardt, Khara M. Sauro, and M. Catherine Bushnell
� � Fibromyalgia: A Disorder of the Brain?
� � Neuroscientist first published on February 12, 2008 as
doi:10.1177/1073858407312521 ?
(For personal use only)

Thank you in advance

Norbert (from Flanders, Belgium)
Please, send to: strandkru...@xxxxxxxxx

It'll cost to get the entire article unless you have a subscription to
Neuroscientist. �However, here's the abstract and contact person if
that will help:

First published on February 12, 2008
The Neuroscientist 2008, doi:10.1177/1073858407312521
(c) 2008 SAGE Publications

--------------------------------------------------------------------------�------

Article

Fibromyalgia: A Disorder of the Brain?
Petra Schweinhardt, Khara M. Sauro, and M. Catherine Bushnell, Ph.D.*
Center for Research on Pain, McGill University

* To whom correspondence should be addressed. E-mail:
catherine.bushn...@xxxxxxxxxx

� Abstract
This article presents evidence that fibromyalgia patients have
alterations in CNS anatomy, physiology, and chemistry that potentially
contribute to the symptoms experienced by these patients. There is
substantial psychophysical evidence that fibromyalgia patients
perceive pain and other noxious stimuli differently than healthy
individuals and that normal pain modulatory systems, such as diffuse
noxious inhibitory control mechanisms, are compromised in
fibromyalgia. Furthermore, functional brain imaging studies revealing
enhanced pain-related activations corroborate the patients' reports of
increased pain. Neurotransmitter studies show that fibromyalgia
patients have abnormalities in dopaminergic, opioidergic, and
serotoninergic systems. Finally, studies of brain anatomy show
structural differences between the brains of fibromyalgia patients and
healthy individuals. The cerebral alterations offer a compelling
explanation for the multiple symptoms of fibromyalgia, including
widespread pain and affective disturbances. The frequent comorbidity
of fibromyalgia with stress-related disorders, such as chronic
fatigue, posttraumatic stress disorder, irritable bowel syndrome, and
depression, as well as the similarity of many CNS abnormalities,
suggests at least a partial common substrate for these disorders.
Despite the numerous cerebral alterations, fibromyalgia might not be a
primary disorder of the brain but may be a consequence of early life
stress or prolonged or severe stress, affecting brain modulatory
circuitry of pain and emotions in genetically susceptible individuals.
NEUROSCIENTIST XX(X):xx-xx, XXXX. DOI: 10.1177/1073858407312521

Hi, Sampatron,

I already got the abstact. But thanks anyway.

Norbert- Hide quoted text -

- Show quoted text -


Well, I tried. *G*

Good luck getting the whole article.

Blissings,
Sam
.

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